Open Access Articles- Top Results for CACNG3


SymbolsCACNG3 ; Cacng2
External IDsOMIM606403 MGI1859165 HomoloGene4767 GeneCards: CACNG3 Gene
RNA expression pattern
File:PBB GE CACNG3 206384 at tn.png
More reference expression data
RefSeq (mRNA)NM_006539NM_019430
RefSeq (protein)NP_006530NP_062303
Location (UCSC)Chr 16:
24.27 – 24.37 Mb
Chr 7:
122.67 – 122.77 Mb
PubMed search[1][2]

Voltage-dependent calcium channel gamma-3 subunit is a protein that in humans is encoded by the CACNG3 gene.[1][2][3]

L-type calcium channels are composed of five subunits. The protein encoded by this gene represents one of these subunits, gamma, and is one of several gamma subunit proteins. It is an integral membrane protein that is thought to stabilize the calcium channel in an inactive (closed) state. This protein is similar to the mouse stargazin protein, mutations in which have been associated with absence seizures, also known as petit-mal or spike-wave seizures. This gene is a member of the neuronal calcium channel gamma subunit gene subfamily of the PMP-22/EMP/MP20 family. This gene is a candidate gene for a familial infantile convulsive disorder with paroxysomal choreoathetosis.[3]

See also


  1. Black JL 3rd, Lennon VA (May 1999). "Identification and cloning of putative human neuronal voltage-gated calcium channel gamma-2 and gamma-3 subunits: neurologic implications". Mayo Clin Proc 74 (4): 357–61. PMID 10221464. doi:10.4065/74.4.357. 
  2. Loftus BJ, Kim UJ, Sneddon VP, Kalush F, Brandon R, Fuhrmann J, Mason T, Crosby ML, Barnstead M, Cronin L, Deslattes Mays A, Cao Y, Xu RX, Kang HL, Mitchell S, Eichler EE, Harris PC, Venter JC, Adams MD (Nov 1999). "Genome duplications and other features in 12 Mb of DNA sequence from human chromosome 16p and 16q". Genomics 60 (3): 295–308. PMID 10493829. doi:10.1006/geno.1999.5927. 
  3. 3.0 3.1 "Entrez Gene: CACNG3 calcium channel, voltage-dependent, gamma subunit 3". 

Further reading


External links

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