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Open Access Articles- Top Results for CD244

CD244

Not to be confused with KIR2DL4.
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Identifiers
SymbolsCD244 ; 2B4; NAIL; NKR2B4; Nmrk; SLAMF4
External IDsOMIM605554 MGI109294 HomoloGene9493 GeneCards: CD244 Gene
RNA expression pattern
File:PBB GE CD244 220307 at tn.png
More reference expression data
Orthologs
SpeciesHumanMouse
Entrez5174418106
EnsemblENSG00000122223ENSMUSG00000004709
UniProtQ9BZW8Q07763
RefSeq (mRNA)NM_001166663NM_018729
RefSeq (protein)NP_001160135NP_061199
Location (UCSC)Chr 1:
160.8 – 160.83 Mb
Chr 1:
171.56 – 171.59 Mb
PubMed search[1][2]

CD244 (Cluster of Differentiation 244) is a human protein encoded by the CD244 gene.[1] It is also known as Natural Killer Cell Receptor 2B4[2]

This gene encodes a cell surface receptor expressed on natural killer cells (NK cells) (and some T cells) mediating non-major histocompatibility complex (MHC) restricted killing. The interaction between NK-cell and target cells via this receptor is thought to modulate NK-cell cytolytic activity. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.[3]


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Further reading

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