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Open Access Articles- Top Results for CD69

CD69

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Identifiers
SymbolsCD69 ; AIM; BL-AC/P26; CLEC2C; EA1; GP32/28; MLR-3
External IDsOMIM107273 MGI88343 HomoloGene128584 GeneCards: CD69 Gene
RNA expression pattern
File:PBB GE CD69 209795 at tn.png
More reference expression data
Orthologs
SpeciesHumanMouse
Entrez96912515
EnsemblENSG00000110848ENSMUSG00000030156
UniProtQ07108P37217
RefSeq (mRNA)NM_001781NM_001033122
RefSeq (protein)NP_001772NP_001028294
Location (UCSC)Chr 12:
9.75 – 9.76 Mb
Chr 6:
129.27 – 129.28 Mb
PubMed search[1][2]

CD69 (Cluster of Differentiation 69) is a human transmembrane C-Type lectin protein encoded by the CD69 gene.

The activation of T lymphocytes and Natural Killer (NK) Cells, both in vivo and in vitro, induces expression of CD69. This molecule, which appears to be the earliest inducible cell surface glycoprotein acquired during lymphoid activation, is involved in lymphocyte proliferation and functions as a signal-transmitting receptor in lymphocytes, including natural killer (NK) cells, and platelets (Cambiaggi et al., 1992) [supplied by OMIM].[1]

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