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Open Access Articles- Top Results for CDX1

CDX1

Template:Infobox3cols/rowTemplate:Infobox3cols/rowTemplate:Infobox3cols/rowTemplate:Infobox3cols/row
Identifiers
SymbolsCDX1 ; MGC116915
External IDsOMIM600746 MGI88360 HomoloGene1366 GeneCards: CDX1 Gene
RNA expression pattern
File:PBB GE CDX1 206430 at tn.png
More reference expression data
Orthologs
SpeciesHumanMouse
Entrez104412590
EnsemblENSG00000113722ENSMUSG00000024619
UniProtP47902P18111
RefSeq (mRNA)NM_001804NM_009880
RefSeq (protein)NP_001795NP_034010
Location (UCSC)Chr 5:
149.55 – 149.56 Mb
Chr 18:
61.02 – 61.04 Mb
PubMed search[1][2]

Homeobox protein CDX-1 is a protein that in humans is encoded by the CDX1 gene.[1][2]

This gene is a member of the caudal-related homeobox transcription factor gene family. The encoded DNA-binding protein regulates intestine-specific gene expression and enterocyte differentiation. It has been shown to induce expression of the intestinal alkaline phosphatase gene, and inhibit beta-catenin/T-cell factor transcriptional activity.[2]

References

  1. ^ Bonner CA, Loftus SK, Wasmuth JJ (Feb 1996). "Isolation, characterization, and precise physical localization of human CDX1, a caudal-type homeobox gene". Genomics 28 (2): 206–11. PMID 8530027. doi:10.1006/geno.1995.1132. 
  2. ^ a b "Entrez Gene: CDX1 caudal type homeobox transcription factor 1". 

Further reading

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External links


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