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Open Access Articles- Top Results for CI-966

CI-966

CI-966
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Other names
1-[2-[bis[4-(Trifluoromethyl)phenyl]methoxy]ethyl]-1,2,5,6-tetrahydropyridine-3-carboxylic acid
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110283-66-4
ChemSpider 171978
Jmol-3D images Image
PubChem Template:Chembox PubChem/format
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C23H21F6NO3
Molar mass 509.87
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
Infobox references

CI-966 is an anticonvulsant, acting as a GABA reuptake inhibitor via blockade of GAT-1.

References

External links

  • Borden LA, Murali Dhar TG, Smith KE, Weinshank RL, Branchek TA, Gluchowski C (October 1994). "Tiagabine, SK&F 89976-A, CI-966, and NNC-711 are selective for the cloned GABA transporter GAT-1". European Journal of Pharmacology 269 (2): 219–24. PMID 7851497. doi:10.1016/0922-4106(94)90089-2. 
  • Phillis JW (September 1995). "CI-966, a GABA uptake inhibitor, antagonizes ischemia-induced neuronal degeneration in the gerbil". General Pharmacology 26 (5): 1061–4. PMID 7557251. doi:10.1016/0306-3623(94)00270-W. 



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