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Open Access Articles- Top Results for CP-1414S

CP-1414S

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CP-1414S
220px
Systematic (IUPAC) name
1-phenyl-4-amino-8-nitro-3H-1,5-benzodiazepin-2-one
Clinical data
Identifiers
36975-99-2 7pxY
None
PubChem CID 37594
ChemSpider 34483 7pxY
Chemical data
Formula C15H12N4O3
296.280
 14pxY (what is this?)  (verify)

CP-1414S is an experimental drug first made by a team in Germany.[1] It is a benzodiazepine derivative. CP-1414S is a 1,5-benzodiazepine, with the nitrogen atoms located at positions 1 and 5 of the diazepine ring, and so is most closely related to other 1,5-benzodiazepines such as clobazam.

CP-1414S has primarily anxiolytic and anticonvulsant effects.[2] Its potency is roughly equal to that of clobazam, but with more pronounced sedation.[3]

See also

References

  1. US 3766169
  2. Carli M, Ballabio M, Caccia S, Garattini S, Samanin R (1981). "Studies on some pharmacological activities of 7-nitro-2-amino-5-phenyl-3H-1,5-benzodiazepine (CP 1414 S) in the rat. A comparison with diazepam". Arzneimittel-Forschung 31 (10): 1721–3. PMID 6119091. 
  3. Mennini T, Garattini S (November 1982). "Benzodiazepine receptors': correlation with pharmacological responses in living animals". Life Sciences 31 (19): 2025–35. PMID 6129557. doi:10.1016/0024-3205(82)90094-7. 



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