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Café au lait spot

Café au lait spot
File:CALSpot.jpg
A café au lait spot on a patient's left cheek.
Classification and external resources
ICD-10 L81.3
ICD-9 709.09
DiseasesDB 16118
eMedicine ped/2754
NCI Café au lait spot
Patient UK Café au lait spot
MeSH D019080

Café au lait spots or café au lait macules are flat, pigmented birthmarks.[1] The name café au lait is French for "coffee with milk" and refers to their light-brown color. They are also called "giraffe spots" or "coast of Maine spots".[2]

They are caused by a collection of pigmented-producing melanocytes in the epidermis of the skin.[3]

These spots are typically permanent, and may grow or increase in number over time.[4]

Cafe au Lait spots are often harmless, but may be associated with syndromes such as Neurofibromatosis Type 1 and McCune-Albright syndrome.[4]

Etiology

Café au lait spots can arise from diverse and unrelated causes:[5][6]

Diagnosis

Diagnosis is visual with measurement of spot size and count of number of spots having clinical significance for diagnosis of associated disorders such as Neurofibromatosis type I. Usually, more than 6 spots more than 3 cm in diameter indicates NF1.

Prognosis

Café au Lait spots are usually present at birth, permanent, and may grow in size or increase in number over time.[4]

Cafe au Lait spots are themselves benign and do not cause any illness or problems. However, they may be associated with syndromes such as Neurofibromatosis Type 1 and McCune-Albright syndrome.[4]

The size and shape of the spots do not have any meaning or implications with regards to diagnosis of associated syndromes.[3]

Treatment

Cafe au lait spots can be removed with lasers.[9] Unfortunately results are variable as the spots are often not completely removed or can come back after treatment. Often, a test spot is treated first to help predict the likelihood of treatment success.[10]

See also

References

  1. Plensdorf S, Martinez J (January 2009). "Common pigmentation disorders". American Family Physician 79 (2): 109–16. PMID 19178061. 
  2. coast of Maine spots - General Practice Notebook
  3. 3.0 3.1 3.2 al.], editors, Lowell A. Goldsmith ... [et (2012). Fitzpatrick's dermatology in general medicine (8th ed. ed.). New York: McGraw-Hill Medical. pp. Chapter 141. ISBN 978-0-07-166904-7. 
  4. 4.0 4.1 4.2 4.3 Morelli, JG (2013). CURRENT Diagnosis & Treatment: Pediatrics, 22e. New York, NY: McGraw-Hill. pp. Chapter 15: Skin. ISBN 978-0-07-182734-8. 
  5. "Cafe Au Lait Spots", by William D James, MD
  6. Cafe Au Lait Spots
  7. Arnsmeier, Sheryl L.; Riccardi, Vincent M.; Paller, Amy S. (1994). "Familial Multiple Cafe au lait Spots". Arch Dermatol. 130 (11): 1425–1426. PMID 7979446. doi:10.1001/archderm.1994.01690110091015. 
  8. Whyte, M. P.; Podgornik, M. N.; Zerega, J.; Reinus, W. R. (2000). "Café-au-lait spots caused by vitiligo in McCune-Albright syndrome". J Bone Miner Res. 15 (12): 2521–2523. PMID 11127218. doi:10.1359/jbmr.2000.15.12.2521. 
  9. Scheinfeld, Noah S. et al. (2011). "Laser Treatment of Benign Pigmented Lesions". MedScape Reference. 
  10. al.], editors, Lowell A. Goldsmith ... [et (2012). Fitzpatrick's dermatology in general medicine (8th ed. ed.). New York: McGraw-Hill Medical. pp. Chapter 239. ISBN 978-0-07-166904-7. 

External links