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Carbocisteine

Carbocisteine
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IUPAC name
(R)-2-Amino-3-(carboxymethylsulfanyl)propanoic acid
Other names
S-Carboxymethyl-L-cysteine; Mucodyne, Solmux, Rhinathiol, Humex, Lisomucil, Fluditec, Exputex, Mucolit, Reodyn, Carbotoux, Flemex, Carbolin, Muflex
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ATC code R05CB03
638-23-3 (R) 7pxY
2387-59-9 (RS)
ChEBI CHEBI:16163 7pxY
ChEMBL ChEMBL396416 7pxY
ChemSpider 168055 7pxY
DrugBank DB04339 7pxY
Jmol-3D images Image
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KEGG D06393 7pxY
PubChem Template:Chembox PubChem/format
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C5H9NO4S
Molar mass Lua error in Module:Math at line 495: attempt to index field 'ParserFunctions' (a nil value). g·mol−1
Appearance Colorless solid
Melting point Script error: No such module "convert".
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Infobox references

Carbocisteine is a mucolytic that reduces the viscosity of sputum and so can be used to help relieve the symptoms of chronic obstructive pulmonary disorder (COPD) and bronchiectasis by allowing the sufferer to bring up sputum more easily. Carbocisteine should not be used with antitussives (cough suppressants) or medicines that dry up bronchial secretions.

Carbocisteine is produced by alkylation of cysteine with chloroacetic acid.[1]

Trade names

  • Fluidol, Humotusin: Romania
  • Rhinathiol: Bulgaria, Congo, Hong Kong, Hungary, Latvia, Lithuania, Malaysia, Oman, Romania, Singapore, South Korea, Switzerland, Taiwan, Thailand, Tunisia, and Vietnam[2]
  • Mucodyne: United Kingdom, India, Ireland, Japan, Netherlands, Serbia.
  • Mucoral: Portugal
  • Mucosol: Egypt
  • Solmux, Loviscol: Philippines

References

  1. ^ Karlheinz Drauz, Ian Grayson, Axel Kleemann, Hans-Peter Krimmer, Wolfgang Leuchtenberger, Christoph Weckbecker “Amino Acids” in Ullmann's Encyclopedia of Industrial Chemistry, 2007, Wiley-VCH, Weinheim. doi:10.1002/14356007.a02_057.pub2
  2. ^ http://www.drugs.com/international/rhinathiol.html