Adverts

Open Access Articles- Top Results for Carbromal

Carbromal

Template:Chembox UNII
Carbromal
Skeletal formula of carbromal
colspan=2 style="background:#f8eaba; border-top:2px solid transparent; border-bottom:2px solid transparent; text-align:center;" #REDIRECTmw:Help:Magic words#Other
This page is a soft redirect. Names

#REDIRECTmw:Help:Magic words#Other
This page is a soft redirect.-

IUPAC name
2-Bromo-N-carbamoyl-2-ethylbutanamide
colspan=2 style="background:#f8eaba; border-top:2px solid transparent; border-bottom:2px solid transparent; text-align:center;" #REDIRECTmw:Help:Magic words#Other
This page is a soft redirect. Identifiers#REDIRECTmw:Help:Magic words#Other
This page is a soft redirect.-


ATC code N05CM04
77-65-6 7pxY
ChEMBL ChEMBL1697828 7pxY
ChemSpider 6243 7pxY
EC number 201-046-6
Jmol-3D images Image
Image
KEGG D02619 7pxY
MeSH carbromal
PubChem Template:Chembox PubChem/format
colspan=2 style="background:#f8eaba; border-top:2px solid transparent; border-bottom:2px solid transparent; text-align:center;" #REDIRECTmw:Help:Magic words#Other
This page is a soft redirect. Properties

#REDIRECTmw:Help:Magic words#Other
This page is a soft redirect.-

C7H13BrN2O2
Molar mass Lua error in Module:Math at line 495: attempt to index field 'ParserFunctions' (a nil value). g·mol−1
Appearance White crystals
Odor Odourless
log P 1.623
Acidity (pKa) 10.69
Basicity (pKb) 3.31
colspan=2 style="background:#f8eaba; border-top:2px solid transparent; border-bottom:2px solid transparent; text-align:center;" #REDIRECTmw:Help:Magic words#Other
This page is a soft redirect. Related compounds

#REDIRECTmw:Help:Magic words#Other
This page is a soft redirect.-


Related ureas
Bromisoval
Related compounds
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
Infobox references

Carbromal is a hypnotic/sedative originally synthesized in 1909 by Bayer.[1]

Synthesis

File:Carbromal synthesis.svg
Carbromal synthesis: DE 225710  (1910);[2][3] Patent literature:[4][5]

Diethylmalonic acid is decarboxylated to 2-ethylvaleric acid then converted via a Hell-Volhard-Zelinsky reaction to α-bromo-α-ethylbutyryl bromide. Reaction with urea with affords carbromal (4).

See also

References

  1. DE 225710 
  2. Frdl. 10, 1160
  3. Chem. Zentralbl. 1910, II, 1008.
  4. Slotta, Grundriss der modernen Arzneistoff-Synthese (Stuttgart, 1931)
  5. H. P. Kaufmann, Arzneimittel-Synthese (Berlin, 1953).


Lua error in package.lua at line 80: module 'Module:Buffer' not found.