Open Access Articles- Top Results for Central canal

Central canal

Central canal of spinal cord
File:Medulla spinalis - Section - English.svg
Cross-section through cervical spinal cord.
File:Medulla spinalis - Substantia grisea - English.svg
Latin canalis centralis medullae spinalis
Gray's p.753
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Anatomical terminology

For the engineering project, see Indiana Central Canal.

The central canal, also known as ependymal canal, is the cerebrospinal fluid-filled space that runs longitudinally through the length of the entire spinal cord. The central canal is continuous with the ventricular system of the brain. The fourth ventricle narrows at a region called the obex to become the central canal of the spinal cord.

The central canal represents the adult remainder of the central cavity of the neural tube. It generally occludes (closes off) with age.[1]


Clinical significance

Syringomyelia is a disease caused by the occlusion of the central canal. Occlusions of the central canal typically occur at the lower cervical and upper thoracic levels. This typically damages white matter fibers that cross in anterior white commissure, leading to the loss of temperature, pain, and motor function at the affected levels on contralateral sides.

See also



  1. ^ Yasui K, Hashizume Y, Yoshida M, Kameyama T, Sobue G (1999). "Age-related morphologic changes of the central canal of the human spinal cord". Acta Neuropathol. 97 (3): 253–9. PMID 10090672. doi:10.1007/s004010050982. 

External links

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