Open Access Articles- Top Results for Chloral betaine

Chloral betaine

Chloral betaine
Systematic (IUPAC) name
(Trimethylammonio)acetate - 2,2,2-trichloro-1,1-ethanediol (1:1)
Clinical data
PubChem CID 16676
DrugBank DB01494
ChemSpider 15813
Chemical data
Formula C7H14Cl3NO4
281.541 g/mol

Chloral betaine (USAN, BAN) (brand names Beta-Chlor, Somilan), also known as cloral betaine (INN), is a sedative-hypnotic drug.[1][2][3][4] It was introduced by Mead Johnson in the United States in 1963.[5] It is a betaine complex form of chloral hydrate, which it is slowly metabolized into and thus is an extended-acting prodrug to, and is then further metabolized into trichloroethanol, which is responsible for most or all of its effects.[3][4][6]

See also


  1. ^ J. Elks (14 November 2014). The Dictionary of Drugs: Chemical Data: Chemical Data, Structures and Bibliographies. Springer. pp. 1231–. ISBN 978-1-4757-2085-3. 
  2. ^ I.K. Morton; Judith M. Hall (6 December 2012). Concise Dictionary of Pharmacological Agents: Properties and Synonyms. Springer Science & Business Media. pp. 72–. ISBN 978-94-011-4439-1. 
  3. ^ a b Ellen L. Bassuk; Stephen C. Schoonover; Alan J. Gelenberg (6 December 2012). The Practitioner's Guide to Psychoactive Drugs. Springer Science & Business Media. pp. 208–. ISBN 978-1-4615-8049-2. 
  4. ^ a b W. Lowry (6 December 2012). Forensic Toxicology: Controlled Substances and Dangerous Drugs. Springer Science & Business Media. pp. 157–. ISBN 978-1-4684-3444-6. 
  5. ^ William Andrew Publishing (22 October 2013). Pharmaceutical Manufacturing Encyclopedia, 3rd Edition. Elsevier. pp. 944–. ISBN 978-0-8155-1856-3. 
  6. ^ George Morrison Maxwell (6 December 2012). Principles of Paediatric Pharmacology. Springer Science & Business Media. pp. 124–. ISBN 978-1-4684-7544-9. 

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