The chloride potassium symporter is a membrane transport protein that is present in the S3-segment of the renal proximal tubule and in the neuron. It functions in renal chloride reabsorption to transport chloride across the basolateral membrane.
They can lower intracellular chloride concentrations below the electrochemical equilibrium potential.
They are of solute carrier family 12.
Types of chloride potassium symporter are:
Each is encoded by a separate gene.
The preceding symporters are actually other types of ion pumps. Member 3, for instance, is the sodium-chloride symporter.
|F-, V-, and A-type ATPase (3.A.2)|
|P-type ATPase (3.A.3)|
- 3.A.3.1.4: H+/K+ transporting, nongastric: ATP12A
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