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Open Access Articles- Top Results for Chlorphenoxamine

Chlorphenoxamine

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Chlorphenoxamine
File:Chlorphenoxamine.svg
Systematic (IUPAC) name
{2-[1-(4-chlorophenyl)-1-phenylethoxy]ethyl}dimethylamine
Clinical data
AHFS/Drugs.com International Drug Names
Oral, topical
Pharmacokinetic data
Bioavailability Well absorbed
Metabolism Likely hepatic
Excretion Renal
Identifiers
77-38-3 7pxY 562-09-4
D04AA34 R06AA06
PubChem CID 6475
DrugBank DB09007 7pxN
ChemSpider 6230 7pxY
UNII 3UVD77BP8R 7pxY
KEGG D07198 7pxY
ChEMBL CHEMBL2110774 7pxN
Chemical data
Formula C18H22ClNO
303.826 g/mol
 14pxN (what is this?)  (verify)

Chlorphenoxamine (Phenoxene) is an antihistamine and anticholinergic used as an antipruritic[1] and antiparkinsonian[2] agent. It is an analog of diphenhydramine.[3]

References

  1. ^ Bazex, A.; Dupre, A.; Christol, B. (1963). "Trial treatment of urticaria with chlorphenoxamine". Clinique (Paris, France) 58: 447–450. PMID 13967113.  edit
  2. ^ Uldall, P. R.; Walton, J. N.; Newell, D. J. (1961). "Chlorphenoxamine hydrochloride in parkinsonism. A controlled trial". British medical journal 1 (5240): 1649–1652. PMC 1954253. PMID 13779077. doi:10.1136/bmj.1.5240.1649.  edit
  3. ^ H. Arnold, N. Brock, E. Kuhas, and D. Lorenz, Arzneimittel Forsch., 4, 189 (1954).


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