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Cinepazet

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Cinepazet
File:Cinepazet.png
Systematic (IUPAC) name
ethyl 2-{4-[(2Z)-3-(3,4,5-trimethoxyphenyl)prop-2-enoyl]piperazin-1-yl}acetate
Clinical data
Identifiers
23887-41-4
C01DX14
PubChem CID 6436156
ChemSpider 4940822
UNII 0LC95WWE9Q 7pxY
ChEMBL CHEMBL2110784
Chemical data
Formula C20H28N2O6
392.45 g/mol
Physical data
Density 1.172 g/cm3

Cinepazet is a vasodilator.

Synthesis

The synthesis of Cinepazet is carried out in two steps, starting with 3,4,5-Trimethoyxcinnamic acid reacting with SOCl2 (thionyl chloride). The product, 3,4,5-Trimethoxycinnamoyl chloride is then reacted with ethyl piperazinoacetate and pyridine.

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Raynaud, G.; Pourias, B.; Fauran, F.; Turin, M.; 1977, U.S. Patent 4,029,650.


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