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Climazolam

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Climazolam
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Systematic (IUPAC) name
8-Chloro-6-(2-chlorophenyl)-1-methyl-4H-imidazo[1,5-a][1,4]benzodiazepine
Clinical data
AHFS/Drugs.com International Drug Names
Identifiers
59467-77-5
QN05CD90
PubChem CID 68790
ChemSpider 62030
UNII O9KZB9HG1Y 7pxY
KEGG D07714
ChEMBL CHEMBL2104070
Chemical data
Formula C18H13Cl2N3
342.222

Climazolam[1] (Ro21-3982) was introduced under licence as a veterinary medicine by the Swiss Pharmacutical company Gräub under the tradename 'Climasol'.[2] Climazolam is a benzodiazepine, specifically an imidazobenzodiazepine derivative developed by Hoffman-LaRoche. It is similar in structure to triazolam and is used in veterinary medicine for anesthetizing animals.[3][4]

References

  1. ^ US 4280957 - Imidazodiazepines and processes therefor
  2. ^ http://www.drugs.com/international/climazolam.html
  3. ^ Ganter M, Kanngiesser M (Aug 1991). "Effect of ketamine and its combinations with xylazine and climazolam on the circulation and respiration in swine". Zentralbl Veterinarmed A (in German) 38 (7): 501–509. PMID 195024. 
  4. ^ Bettschart-Wolfensberger R, Taylor PM, Sear JW, Bloomfield MR, Rentsch K, Dawling S (Oct 1996). "Physiologic effects of anesthesia induced and maintained by intravenous administration of a climazolam-ketamine combination in ponies premedicated with acepromazine and xylazine". American Journal of Veterinary Research 57 (10): 1472–1427. PMID 8896687. 

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