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Open Access Articles- Top Results for Clortermine

Clortermine

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Clortermine
File:Clortermine.svg
Systematic (IUPAC) name
1-(2-chlorophenyl)-2-methylpropan-2-amine
Clinical data
  •  ?
  • (Prescription only)
Oral
Identifiers
10389-73-8 7pxN
None
PubChem CID 25223
DrugBank DB01527 7pxY
ChemSpider 23558 7pxY
UNII 4FA88HM3IX 7pxY
KEGG D03566 7pxY
ChEMBL CHEMBL1697833 7pxN
Synonyms 2-chloro-α,α-dimethylphenethylamine;
2-chloro-α-methylamphetamine;
2-chlorophentermine
Chemical data
Formula C10H14ClN
183.68 g/mol
 14pxN (what is this?)  (verify)

Clortermine (Voranil) was developed by Ciba in the 1960s[1] and is an anorectic drug of the amphetamine class.[2] It is the 2-chloro analogue of the better known appetite suppressant phentermine, and is the 2-chloro positional isomer of chlorphentermine. Clortermine produces very low rates of self-administration in animals similarly to chlorphentermine,[3] and as a result it likely does not act on dopamine. Instead, it may act as a serotonin and/or norepinephrine releasing agent.[citation needed]

See also

References

  1. US patent 3415937, "The Suppression of Appetite with 1-(o-Chlorophenyl)-2-Methyl-2-Propylamine" 
  2. Triggle, D. J. (1996). Dictionary of Pharmacological Agents. Boca Raton: Chapman & Hall / CRC. ISBN 0-412-46630-9. 
  3. Sannerud, C. A.; Brady, J. V.; Griffiths, R. R. (1989). "Self-Injection in Baboons of Amphetamines and Related Designer Drugs". NIDA Research Monograph 94: 30–42. PMID 2514366.