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Open Access Articles- Top Results for Collagen, type VIII, alpha 1

Collagen, type VIII, alpha 1

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Identifiers
SymbolsCOL8A1 ; C3orf7
External IDsOMIM120251 MGI88463 HomoloGene22423 GeneCards: COL8A1 Gene
RNA expression pattern
File:PBB GE COL8A1 221152 at tn.png
More reference expression data
Orthologs
SpeciesHumanMouse
Entrez129512837
EnsemblENSG00000144810ENSMUSG00000068196
UniProtP27658Q00780
RefSeq (mRNA)NM_001850NM_007739
RefSeq (protein)NP_001841NP_031765
Location (UCSC)Chr 3:
99.36 – 99.52 Mb
Chr 16:
57.62 – 57.75 Mb
PubMed search[1][2]

Collagen alpha-1(VIII) chain is a protein that in humans is encoded by the COL8A1 gene.[1][2]

This gene encodes one of the two alpha chains of type VIII collagen. The gene product is a short chain collagen and a major component of the basement membrane of the corneal endothelium. The type VIII collagen fibril can be either a homo- or a heterotrimer. Alternatively spliced transcript variants encoding the same isoform have been observed.[2]

References

  1. ^ Muragaki Y, Mattei MG, Yamaguchi N, Olsen BR, Ninomiya Y (Jun 1991). "The complete primary structure of the human alpha 1 (VIII) chain and assignment of its gene (COL8A1) to chromosome 3". Eur J Biochem 197 (3): 615–22. PMID 2029894. doi:10.1111/j.1432-1033.1991.tb15951.x. 
  2. ^ a b "Entrez Gene: COL8A1 collagen, type VIII, alpha 1". 

Further reading

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