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Combined injectable contraceptive

Combined Injectable Contraceptive
Birth control type Hormonal
First use about 1980
Failure rates (first year)
Perfect use 0-0.2%[1]
Typical use ?
Duration effect 1 month
User reminders ?
Advantages and disadvantages
STD protection No
Benefits Especially good if poor pill compliance.

Combined injectable contraceptive (CIC) monthly injection of a progestin and a synthetic estrogen taken to suppress fertility. Brand names include Cyclofem, Novafem, Mesigyna, Lunelle and Cyclo-Provera.

DMPA is a different injectable contraceptive, containing just a progestin, given every three months.


  • October 5, 2000, Pharmacia received FDA approval for Lunelle Monthly Contraceptive Injection.[1]
  • April 2003, Pharmacia acquired by Pfizer (makers of Depo-Provera (DMPA)).
  • October 2003, Lunelle was discontinued in the U.S.

Use and packaging

Administered by intramuscular injection into the deltoid, gluteus maximus, or anterior thigh.[1] Ideally administered every 28 to 30 days, though demonstrated to be effective up to 33 days.[1]


The most prominent side effects are menstrual irregularities during the first 3 to 6 months of use.[1]


See also


  1. ^ a b c d e f "FDA Approves Combined Monthly Injectable Contraceptive". Contraception Report 12 (3). 2001. [dead link]

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