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Open Access Articles- Top Results for D-161

D-161

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D-161
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Systematic (IUPAC) name
4-((((3S,6S)-6-benzhydryltetrahydro-2H-pyran-3-yl)amino)methyl)phenol
Clinical data
Identifiers
PubChem CID 11545250
ChemSpider 9720029
Chemical data
Formula C25H27NO2
373.486 g/mol
 14pxY (what is this?)  (verify)

D-161[1] is a chemical known in research circles as a triple reuptake inhibitor. Although this compound has lent support to the inclusion of dopamine in the monoamine hypothesis of depression, D-161 has not been tested in clinical trials.

References

  1. ^ Dutta, A.; Ghosh, B.; Biswas, S.; Reith, M. (2008). "D-161, a novel pyran-based triple monoamine transporter blocker: behavioral pharmacological evidence for antidepressant-like action". European Journal of Pharmacology 589 (1–3): 73–79. PMID 18561912. doi:10.1016/j.ejphar.2008.05.008.  edit