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DSP-4
For the Super NES enhancement chip, see List of Super NES enhancement chips#DSP.
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IUPAC name
N-(2-Chloroethyl)-N-ethyl-2-bromobenzylamine
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ChemSpider | 3060 |
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| Jmol-3D images | Image | |
| PubChem | Template:Chembox PubChem/format | |
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C11H15BrClN | |
| Molar mass | 276.60 g/mol | |
| Density | 1.339 g/cm3 | |
| Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). | ||
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DSP-4, also known as N-(2-chloroethyl)-N-ethyl-2-bromobenzylamine, is a neurotoxin selective for noradrenergic neurons, capable of crossing the blood–brain barrier.[1]
It exerts transient effects in peripheral sympathetic neurons, but more permanent changes within neurons of the central nervous system. It can induce long-term depletion in cortical and spinal levels of noradrenaline.[2]
See also
References
- ^ Daw NW, Videen TO, Parkinson D, Rader RK (1985). "DSP-4 (N-(2-Chloroethyl)-N-ethyl-2-bromobenzylamine) Depletes Noradrenaline in Kitten Visual Cortex Without Altering the Effects of Monocular Deprivation". J. Neurosci 5 (7): 1925–1933. PMID 3926960.
- ^ Jaim-Etcheverry G, Mari´a Zieher L (1980). "DSP-4: A novel compound with neurotoxic effects on noradrenergic neurons of adult and developing rats". Brain Res. 188 (2): 513–523. PMID 7370771. doi:10.1016/0006-8993(80)90049-9.
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