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Open Access Articles- Top Results for DYNLRB1

DYNLRB1

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Identifiers
SymbolsDYNLRB1 ; BITH; BLP; DNCL2A; DNLC2A; ROBLD1
External IDsOMIM607167 MGI1914318 HomoloGene69161 GeneCards: DYNLRB1 Gene
Orthologs
SpeciesHumanMouse
Entrez8365867068
EnsemblENSG00000125971ENSMUSG00000047459
UniProtQ9NP97P62627
RefSeq (mRNA)NM_001281727NM_001291108
RefSeq (protein)NP_001268656NP_001278037
Location (UCSC)Chr 20:
33.1 – 33.13 Mb
Chr 2:
155.24 – 155.25 Mb
PubMed search[1][2]

Dynein light chain roadblock-type 1 is a protein that in humans is encoded by the DYNLRB1 gene.[1][2][3]

This gene is a member of the roadblock dynein light chain family and encodes a cytoplasmic protein that is capable of binding intermediate chain proteins. Upregulation of this gene has been associated with hepatocellular carcinomas, suggesting that this gene may be involved in tumor progression.[3]

References

  1. ^ Jiang J, Yu L, Huang X, Chen X, Li D, Zhang Y, Tang L, Zhao S (Dec 2001). "Identification of two novel human dynein light chain genes, DNLC2A and DNLC2B, and their expression changes in hepatocellular carcinoma tissues from 68 Chinese patients". Gene 281 (1–2): 103–13. PMID 11750132. doi:10.1016/S0378-1119(01)00787-9. 
  2. ^ Pfister KK, Fisher EM, Gibbons IR, Hays TS, Holzbaur EL, McIntosh JR, Porter ME, Schroer TA, Vaughan KT, Witman GB, King SM, Vallee RB (Nov 2005). "Cytoplasmic dynein nomenclature". J Cell Biol 171 (3): 411–3. PMC 2171247. PMID 16260502. doi:10.1083/jcb.200508078. 
  3. ^ a b "Entrez Gene: DYNLRB1 dynein, light chain, roadblock-type 1". 

Further reading

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