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Open Access Articles- Top Results for Demexiptiline

Demexiptiline

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Demexiptiline
Skeletal formula of demexiptiline
Space-filling model of the demexiptiline molecule
Systematic (IUPAC) name
5H-dibenzo(a,d)cyclohepten-5-one O-(2-(methylamino)ethyl)oxime
Clinical data
  • (Prescription only)
Oral
Identifiers
18059-99-9
None
PubChem CID 28876
DrugBank DB08998 7pxY
ChemSpider 26858
UNII EYX738UZ5P 7pxY
ChEMBL CHEMBL2107576
Chemical data
Formula C18H18N2O
278.35 g/mol

Demexiptiline (Deparon, Tinoran) is a tricyclic antidepressant (TCA) used in France for the treatment of depression.[1][2] It acts primarily as a norepinephrine reuptake inhibitor similarly to desipramine.[3]

References

  1. ^ Swiss Pharmaceutical Society (2000). Index Nominum 2000: International Drug Directory (Book with CD-ROM). Boca Raton: Medpharm Scientific Publishers. p. 301. ISBN 3-88763-075-0. 
  2. ^ David J. Triggle (1996). Dictionary of Pharmacological Agents. Boca Raton: Chapman & Hall/CRC. p. 583. ISBN 0-412-46630-9. 
  3. ^ Teste JF, Pelsy-Johann I, Decelle T, Boulu RG (1993). "Anti-immobility activity of different antidepressant drugs using the tail suspension test in normal or reserpinized mice". Fundamental & Clinical Pharmacology 7 (5): 219–26. PMID 8370568. doi:10.1111/j.1472-8206.1993.tb00235.x. 

Further reading

  • Martin A, Masson JM, Jusseaume P, Beloncle M, Voisinet C (November 1981). "[Demexiptiline in the treatment of melancholic states (reflections after 3 years of use)]". Annales Médico-psychologiques (in French) 139 (9): 1023–35. 


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