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Open Access Articles- Top Results for Deoxyadenosine

Deoxyadenosine

Template:Chembox UNII
Deoxyadenosine
Skeletal formula of deoxyadenosine
Space-filling model of the deoxyadenosine molecule
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This page is a soft redirect. Names

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IUPAC name
5-(6-Aminopurin-9-yl)-2-(hydroxymethyl)oxolan-3-ol
Other names
2'-Deoxyadenosine; α-Deoxyadenosine; dA
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958-09-8 7pxY
ChEBI CHEBI:17256 7pxY
ChEMBL ChEMBL416340 7pxN
ChemSpider 13135 7pxY
Jmol-3D images Image
MeSH 2'-deoxyadenosine
PubChem Template:Chembox PubChem/format
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C10H13N5O3
Molar mass 251.24192
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
 14pxN verify (what is10pxY/10pxN?)
Infobox references

Deoxyadenosine is a deoxyribonucleoside. It is a derivative of the nucleoside adenosine, differing from the latter by the replacement of a hydroxyl group (-OH) by hydrogen (-H) at the 2' position of its ribose sugar moiety. Deoxyadenosine is the DNA nucleoside A, which pairs with deoxythymidine (T) in double-stranded DNA. In absence of adenosine deaminase (ADA) it accumulates in T lymphocytes and kills these cells resulting in a genetic disorder known as adenosine deaminase severe combined immunodeficiency disease (ADA-SCID).[1]

See also

References

  1. ^ Griffiths, Anthony J. F.; Wessler, Susan R.; Carroll, Sean B.; Doebly, John (2012). Introduction to Genetic Analysis (10th ed.). New York: W . H. Freeman and Company. ISBN 1-4641-0661-4.