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Diaminopimelic acid

Diaminopimelic acid
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IUPAC name
(2R,6S)-2,6-Diaminoheptanedioic acid
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583-93-7 7pxN
ChEBI CHEBI:16488 7pxY
ChEMBL ChEMBL415306 7pxY
ChemSpider 89700 7pxY
Jmol-3D images Image
MeSH Diaminopimelic+acid
PubChem Template:Chembox PubChem/format
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C7H14N2O4
Molar mass Lua error in Module:Math at line 495: attempt to index field 'ParserFunctions' (a nil value). g·mol−1
Appearance white powder
Density 1.344 g/mL
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Main hazards Irritant
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Infobox references

Diaminopimelic acid (DAP) is an amino acid, representing an epsilon-carboxy derivative of lysine.

DAP is a characteristic of certain cell walls[1] of some bacteria. DAP is often found in the peptide linkages of NAM-NAG chains that make up the cell wall of gram-negative bacteria. When provided, they exhibit normal growth. When in deficiency, they still grow but with the inability to make new cell wall proteoglycan.

This is also the attachment point for Braun's lipoprotein.[2]

See also

Images

File:DAP-H.png
An alternate view of the DAP structure.

References

  1. ^ Brooks, George H.; Geo F. Brooks (2007). Jawetz, Melnick & Adelberg's medical microbiology. McGraw-Hill Medical. p. 85. ISBN 0-07-147666-0. 
  2. ^ Seltmann, Guntram; Holst, Otto (2002). The Bacterial Cell Wall. Berlin: Springer. pp. 81–82. ISBN 3-540-42608-6. 

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