Journals

Dichloroisoprenaline

200px
colspan=2 style="background:#f8eaba; border-top:2px solid transparent; border-bottom:2px solid transparent; text-align:center;" #REDIRECTmw:Help:Magic words#Other This page is a soft redirect. Names #REDIRECTmw:Help:Magic words#Other This page is a soft redirect.-	Preferred IUPAC name Dichloroisoprenaline
Systematic IUPAC name 1-(3,4-Dichlorophenyl)-2-[(propan-2-yl)amino]ethan-1-ol
Other names 1-(3,4-Dichlorophenyl)-2-(isopropylamino)ethanol Dichlorisoproterenol
colspan=2 style="background:#f8eaba; border-top:2px solid transparent; border-bottom:2px solid transparent; text-align:center;" #REDIRECTmw:Help:Magic words#Other This page is a soft redirect. Identifiers#REDIRECTmw:Help:Magic words#Other This page is a soft redirect.-	CAS Registry Number	59-61-0 7pxN
ChEBI	CHEBI:144234 7pxN
ChEMBL	ChEMBL30816 7pxY
ChemSpider	5601 (1R) 7pxY 5324297 (1S) 7pxY 5601 () 7pxY
InChI InChI=1S/C11H15Cl2NO/c1-7(2)14-6-11(15)8-3-4-9(12)10(13)5-8/h3-5,7,11,14-15H,6H2,1-2H3 7pxY Key: VKMGSWIFEHZQRS-UHFFFAOYSA-N 7pxY InChI=1/C11H15Cl2NO/c1-7(2)14-6-11(15)8-3-4-9(12)10(13)5-8/h3-5,7,11,14-15H,6H2,1-2H3 Key: VKMGSWIFEHZQRS-UHFFFAOYAS
Jmol-3D images	Image Image
KEGG	C11772 7pxN
MeSH	Dichloroisoproterenol
PubChem	Template:Chembox PubChem/formatTemplate:Chembox PubChem/formatTemplate:Chembox PubChem/format
SMILES Template:Chembox SMILES/format Template:Chembox SMILES/format
colspan=2 style="background:#f8eaba; border-top:2px solid transparent; border-bottom:2px solid transparent; text-align:center;" #REDIRECTmw:Help:Magic words#Other This page is a soft redirect. Properties #REDIRECTmw:Help:Magic words#Other This page is a soft redirect.-	Chemical formula	C11H15Cl2NO
Molar mass	248.15 g/mol
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
14pxN verify (what is: 10pxY/10pxN?)
Infobox references

Dichloroisoprenaline (DCI), also known as dichloroisoproterenol, was the first beta blocker ever to be developed. It is non-selective for the β₁-adrenergic and β₂-adrenergic receptors. DCI has low potency and acts as a partial agonist/antagonist at these receptors.

Although DCI was of no clinical value itself, further developments from DCI eventually led to the development of the clinical candidate pronethalol (withdrawn due to carcinogenicity) and subsequently propranolol (the first clinically successful beta blocker).

Dichloroisoprenaline is a racemic mixture of enantiomers.

File:(±)-Dichlorosisoproterenol Enantiomers Structural Formulae.png

The two enantiomers of dichloroisoprenaline