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Open Access Articles- Top Results for Difetarsone

Difetarsone

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Difetarsone
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Systematic (IUPAC) name
[4-[2-[(4-arsonophenyl)amino]ethylamino]phenyl] arsonic acid
Clinical data
Identifiers
3639-19-8
P01AR02 QP51AD02
PubChem CID 68199
ChemSpider 61506
UNII G4G9J3Q65W 7pxY
KEGG D07357
Chemical data
Formula C14H18As2N2O6
460.146 g/mol

Difetarsone is an antiprotozoal agent. Various studies have shown it to be particularly effective against Trichuris trichiura, commonly known as the whipworm. Prior to the drugs use in the early 1970s, there were few effective treatments for this infection.[1] It has also been used to treat Entamoeba histolytica infections.[2]

Difetarsone often has minor side effects, which include rashes, nausea and vomiting. It has also resulted in angioedema in at least one known case.[2]

References

  1. ^ P.M. Leary; C. Jones; F. Douglas; S.T. Boyd (June 1972). "Difetarsone in Difetarsone in outpatient treatment of Trichuris trichiura infestation". Archives of Disease in Childhood 49 (6): 486–8. PMC 1648795. PMID 4851370. Retrieved October 6, 2013. 
  2. ^ a b Jeffrey K. Aronson (2009). Meyler's Side Effects of Antimicrobial Drugs. p. 834. ISBN 9780080932934. Retrieved October 7, 2013. 


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