Open Access Articles- Top Results for Dimemebfe


Systematic (IUPAC) name
Clinical data
  • US: Not FDA approved; unscheduled
140853-58-3 7pxY
PubChem CID 126589
ChemSpider 112474 7pxN
Synonyms 5-MeO-BFE
Chemical data
Formula C13H17NO2
219.279 g/mol
 14pxN (what is this?)  (verify)

Dimemebfe (5-MeO-BFE) is a recreational drug[1] and research chemical. It acts as an agonist for the 5-HT1A and 5-HT2 family of serotonin receptors. It is related in structure to the psychedelic tryptamine derivative 5-MeO-DMT, but with the indole nitrogen replaced by oxygen, making dimemebfe a benzofuran derivative. It is several times less potent as a serotonin agonist than 5-MeO-DMT and with relatively more activity at 5-HT1A, but still shows strongest effects at the 5-HT2 family of receptors.[2]


  1. ^ John F. Casale and Patrick A. Hays. "The Characterization of 2-(5-Methoxy-1-benzofuran-3-yl)-N,N-dimethylethanamine (5-MeO-BFE) and Differentiation from its N-Ethyl Analog" (PDF). Microgram Journal 9 (1): 39–45. 
  2. ^ Tomaszewski, Z.; Johnson, M. P.; Huang, X.; Nichols, D. E. (1992). "Benzofuran bioisosteres of hallucinogenic tryptamines". Journal of Medicinal Chemistry 35 (11): 2061–2064. PMID 1534585. doi:10.1021/jm00089a017. 

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