Systematic (IUPAC) name
Clinical data
PubChem CID 24257269
ChemSpider 23553090 7pxY
Chemical data
Formula C12H17NO2
207.269 g/mol
 14pxY (what is this?)  (verify)
This article is about the amphetamine. For other uses, see EDMA (disambiguation).

3,4-Ethylenedioxy-N-methylamphetamine (EDMA) is an entactogen drug of the amphetamine class.[1][2] It is an analogue of MDMA where the methylenedioxy ring has been replaced by an ethylenedioxy ring.[1][2] EDMA was first synthesized by Alexander Shulgin.[1] In his book PiHKAL, the dosage is listed as 150–250 mg, and the duration listed as 3–5 hours.[1] According to Shulgin, EDMA produces a bare threshold consisting of paresthesia, nystagmus, and hypnogogic imagery, with few to no other effects.[1] Scientific research has demonstrated that EDMA acts as a non-neurotoxic serotonin releasing agent with moderately diminished potency relative to MDMA, and with negligible effects on dopamine release.[2] Based on Shulgin's reports of essential inactivity at 150–250 mg, it may be more active at higher doses.

See also


  1. ^ a b c d e Ann Shulgin; Alexander Shulgin (1991). Pihkal: A Chemical Love Story. Transform Press. ISBN 0-9630096-0-5. 
  2. ^ a b c McKenna DJ, Guan XM, Shulgin AT (March 1991). "3,4-Methylenedioxyamphetamine (MDA) analogues exhibit differential effects on synaptosomal release of 3H-dopamine and 3H-5-hydroxytryptamine". Pharmacology, Biochemistry, and Behavior 38 (3): 505–12. PMID 1829838. doi:10.1016/0091-3057(91)90005-M. 

External links