Open Access Articles- Top Results for EGIS-7625


EGIS-7625 (C18H22N4O2) is a selective and competitive receptor antagonist and Synthetic organic compound.[1] It is experimentally proven to be directly associated with smooth stomach muscle construction of white rats in vivo, and variably effective in provoking a similar response in in vitro human stomach cells.[2] In high blood concentrations, it causes mild constriction of rabbit pulmonary arteries.[2]


  1. ^ PubChem 9930789
  2. ^ a b Kovács, Anikó; Gacsályi, Istvan; Wellmann, János; Schmidt, Éva; Szücs, Zsuzsanna; Dubreuil, Valérie; Nicolas, Jean Paul; Boutin, Jean et al. (2003). "Effects of EGIS-7625, a Selective and Competitive 5-HT2B Receptor Antagonist". Cardiovascular Drugs and Therapy 17 (5/6): 427–34. PMID 15107597. doi:10.1023/B:CARD.0000015857.96371.43.