Adverts

Open Access Articles- Top Results for EIF2AK4

EIF2AK4

Template:Infobox3cols/rowTemplate:Infobox3cols/rowTemplate:Infobox3cols/rowTemplate:Infobox3cols/row
Identifiers
SymbolsEIF2AK4 ; GCN2; PVOD2
External IDsOMIM609280 MGI1353427 HomoloGene40891 IUPHAR: 2018 ChEMBL: 5358 GeneCards: EIF2AK4 Gene
EC number2.7.11.1
Orthologs
SpeciesHumanMouse
Entrez44027527103
EnsemblENSG00000128829ENSMUSG00000005102
UniProtQ9P2K8Q9QZ05
RefSeq (mRNA)NM_001013703NM_001177806
RefSeq (protein)NP_001013725NP_001171277
Location (UCSC)Chr 15:
40.23 – 40.33 Mb
Chr 2:
118.39 – 118.48 Mb
PubMed search[1][2]

Eukaryotic translation initiation factor 2-alpha kinase 4 is an enzyme that in humans is encoded by the EIF2AK4 gene.[1][2]

EIF2AK4 belongs to a family of kinases that phosphorylate the alpha subunit of eukaryotic translation initiation factor-2 (EIF2S1; MIM 603907) to downregulate protein synthesis in response to varied cellular stresses (Berlanga et al., 1999).[supplied by OMIM][2]

See also

References

  1. ^ Berlanga JJ, Santoyo J, De Haro C (Nov 1999). "Characterization of a mammalian homolog of the GCN2 eukaryotic initiation factor 2alpha kinase". Eur J Biochem 265 (2): 754–62. PMID 10504407. doi:10.1046/j.1432-1327.1999.00780.x. 
  2. ^ a b "Entrez Gene: EIF2AK4 eukaryotic translation initiation factor 2 alpha kinase 4". 

Further reading

</dl>

Template:Gene-15-stub