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Open Access Articles- Top Results for EMPA (drug)

EMPA (drug)

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EMPA
File:EMPA.svg
Systematic (IUPAC) name
N-Ethyl-N2-(6-methoxy-3-pyridinyl)-N2-[(2-methylphenyl)sulfonyl]-N-(3-pyridinylmethyl)glycinamide
Clinical data
Identifiers
680590-49-2
None
PubChem CID 9981404
ChemSpider 8156996
Chemical data
Formula C23H26N4O4S
454.542 g/mol

EMPA is a selective antagonist of the OX2 receptor, with 900-fold selectivity in binding for OX2 over OX1.[1] [2]

See also

References

  1. ^ "Biochemical and Electrophysiological Characterization of Almorexant, a Dual Orexin 1 Receptor (OX1)/Orexin 2 Receptor (OX2) Antagonist: Comparison with Selective OX1 and OX2 Antagonists", [1], Pari Malherbe, Edilio Borroni, Emmanuel Pinard, Joseph G. Wettstein, and Frederic Knoflach, in Molecular Pharmacology, , 2009
  2. ^ Malherbe et al (2009) Biochemical and behavioural characterization of EMPA, a novel high-affinity, selective antagonist for the OX2 receptor. Br.J.Pharmacol. 156 1326. PMID: 19751316. edit



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