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Open Access Articles- Top Results for EPHA7

EPHA7

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Identifiers
SymbolsEPHA7 ; EHK-3; EHK3; EK11; HEK11
External IDsOMIM602190 MGI95276 HomoloGene20935 IUPHAR: 1827 ChEMBL: 4602 GeneCards: EPHA7 Gene
EC number2.7.10.1
RNA expression pattern
File:PBB GE EPHA7 206852 at tn.png
More reference expression data
Orthologs
SpeciesHumanMouse
Entrez204513841
EnsemblENSG00000135333ENSMUSG00000028289
UniProtQ15375Q61772
RefSeq (mRNA)NM_001288629NM_001122889
RefSeq (protein)NP_001275558NP_001116361
Location (UCSC)Chr 6:
93.95 – 94.13 Mb
Chr 4:
28.81 – 28.97 Mb
PubMed search[1][2]

Ephrin type-A receptor 7 is a protein that in humans is encoded by the EPHA7 gene.[1][2]

This gene belongs to the ephrin receptor subfamily of the protein-tyrosine kinase family. EPH and EPH-related receptors have been implicated in mediating developmental events, particularly in the nervous system. Receptors in the EPH subfamily typically have a single kinase domain and an extracellular region containing a Cys-rich domain and 2 fibronectin type III repeats. The ephrin receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands.[2]

References

  1. ^ Ephnomenclaturecommittee (Sep 1997). "Unified nomenclature for Eph family receptors and their ligands, the ephrins. Eph Nomenclature Committee". Cell 90 (3): 403–4. PMID 9267020. doi:10.1016/S0092-8674(00)80500-0. 
  2. ^ a b "Entrez Gene: EPHA7 EPH receptor A7". 

Further reading

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