Open Access Articles- Top Results for Emylcamate


Systematic (IUPAC) name
3-methyl-3-pentanol carbamate
Clinical data
78-28-4 7pxY
PubChem CID 6526
ChemSpider 6278 7pxY
UNII KCJ747D3R4 7pxY
KEGG D07317 7pxY
Chemical data
Formula C7H15NO2
 14pxY (what is this?)  (verify)

Emylcamate (marketed as Striatran by Merck) is an anxiolytic and muscle relaxant. It was patented in the US in 1961 (US Patent 2,972,564) and advertised for the treatment of anxiety and tension. It was claimed to be superior to meprobamate, which was the market leader at the time. It is no longer prescribed.

A study of the drug's effects in mice was done in 1959. It concluded that at 50 mg/kg emylcamate gave a 63% decrease in motor activity compared to meprobamate's 32% decrease, a doubling in effective potency. The therapeutic index in mice was also established:

Meprobamate Emylcamate Effect
175 123 ED50 (mg/kg)
600 550 LD50 (mg/kg)
3.4 4.4 Therapeutic index

Emylcamate also has a faster intra-parenteral onset then meprobabamate, 3 minutes compared to 35. [1]


  1. Melander, B. (1959). "Emylcamate, A Potent Tranquillizing Relaxant". Journal of Medicinal and Pharmaceutical Chemistry 1 (5): 443–457. doi:10.1021/jm50006a003.  edit

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