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Open Access Articles- Top Results for Encainide

Encainide

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Encainide
File:EncainideRedrawn.svg
Systematic (IUPAC) name
4-methoxy-N-[2-(1-methyl-2-piperidin-1-ylethyl)phenyl]benzamide
Clinical data
Trade names Enkaid
AHFS/Drugs.com Micromedex Detailed Consumer Information
MedlinePlus a605040
  • Withdrawn
Identifiers
66778-36-7 7pxY
C01BC08
PubChem CID 48041
DrugBank DB01228 7pxY
ChemSpider 43697 7pxY
UNII SY3J0147NB 7pxY
KEGG D07894 7pxY
ChEBI CHEBI:4788 7pxY
ChEMBL CHEMBL315838 7pxN
Chemical data
Formula C22H28N2O2
352.47 g/mol
 14pxN (what is this?)  (verify)

Encainide (trade name Enkaid) is a class Ic antiarrhythmic agent. It is no longer used because of its frequent proarrhythmic side effects.[1]

Synthesis

Lidamidine

See also

References

  1. ^ Echt, D. S.; Liebson, P. R.; Mitchell, L. B.; Peters, R. W.; Obias-Manno, D.; Barker, A. H.; Arensberg, D.; Baker, A.; Friedman, L.; Greene, H. L.; Huther, M. L.; Richardson, D. W. (1991). "Mortality and Morbidity in Patients Receiving Encainide, Flecainide, or Placebo". New England Journal of Medicine 324 (12): 781–788. PMID 1900101. doi:10.1056/NEJM199103213241201.  edit
  2. ^ S.J. Dykstra, J.L. Minelli, DE 2210154  (1972).
  3. ^ S.J. Dykstra, J.L. Minelli, U.S. Patent 3,931,195 (1976).
  4. ^ Dykstra, Stanley J. (1973). "Lysergic acid and quinidine analogs. 2-(o-Acylaminophenethyl)piperidines". Journal of Medicinal Chemistry 16 (9): 1015–1020. doi:10.1021/jm00267a012.  edit


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