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Open Access Articles- Top Results for Enprofylline

Enprofylline

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Enprofylline
200px
Systematic (IUPAC) name
3-propyl-7H-purine-2,6-dione
Clinical data
Identifiers
41078-02-8 7pxY
PubChem CID 1676
DrugBank DB00824 7pxN
ChemSpider 1613 7pxY
UNII DT7DT5E518 7pxN
ChEBI CHEBI:126237 7pxN
ChEMBL CHEMBL279898 7pxN
Chemical data
Formula C8H10N4O2
194.190 g/mol
 14pxN (what is this?)  (verify)

Enprofylline (3-Propylxanthine) is a xanthine derivative used in the treatment of asthma, which acts as a bronchodilator. It acts primarily as a competitive nonselective phosphodiesterase inhibitor with relatively little activity as a nonselective adenosine receptor antagonist.[1][2]


References

  1. ^ Lunell E, Svedmyr N, Andersson KE, Persson CG (1982). "Effects of enprofylline, a xanthine lacking adenosine receptor antagonism, in patients with chronic obstructive lung disease". European Journal of Clinical Pharmacology 22 (5): 395–402. PMID 6288396. doi:10.1007/bf00542541. 
  2. ^ Laursen LC (December 1987). "Anti asthmatic effects and pharmacokinetics of enprofylline--a new xanthine derivate". Danish Medical Bulletin 34 (6): 289–97. PMID 3325233.