Open Access Articles- Top Results for Eprobemide


Systematic (IUPAC) name
Clinical data
Trade names Befol (RU)
  • (Prescription only)
PubChem CID 65659
ChemSpider 59094
Synonyms Befol
Chemical data
Formula C14H19ClN2O2
282.77 g/mol

Eprobemide (INN) is a pharmaceutical drug that was used as an antidepressant in Russia (under the brand name Befol).[1] It is a non-competitive reversible inhibitor of monoamine oxidase A[2][3] that exhibits selective action on serotonin deamination.[4] Eprobemide differs from moclobemide only in linker that connects morpholine fragment with chlorobenzamide—moclobemide has two carbon atoms while eprobemide has three. Its registration was cancelled on December 30, 2003.[5]


  1. ^ C.R. Ganellin, David J. Triggle (1996). Dictionary of Pharmacological Agents 3. p. 811. ISBN 978-0412466304. 
  2. ^ Gol'dina, O.A.; Moskvitina, T.A.; Gankina, E.M.; Kirkel', A.Z.; Kamyshanskaia, N.S.; Lopatina, K.I.; Sokolova, T.V.; Zagorevskiĭ, V.A.; Val'dman, A.V.; Gorkin, V.Z. (1991). "The action of befol and its derivatives on monoamine oxidase of different origins". Biulleten' eksperimental'noi biologii i meditsiny 111 (3): 279–280. PMID 2054504. 
  3. ^ Donskaya, N.S.; Antonkina, O.A.; Glukhan, E. N.; Smirnov, S. K. (2004-07-01). "Antidepressant Befol Synthesized Via Interaction of 4-Chloro-N-(3-chloropropyl)benzamide with Morpholine". Pharmaceutical Chemistry Journal. 0091-150X (Kluwer Academic Publishers-Plenum Publishers) 38 (7): 381–384. doi:10.1023/B:PHAC.0000048439.38383.5f. 
  4. ^ Eprobemide, ChemIDplus
  5. ^ "Befol — 4DOKTOR.RU Drug Information Handbook" (in Russian). Retrieved 4 February 2014. 

Lua error in package.lua at line 80: module 'Module:Buffer' not found.