Essential oil - Related Links
Open Access Articles- Top Results for Essential oil
Journal of Environmental Analytical ChemistryDetecting Essential Oil Adulteration
International Journal of Plant, Animal and Environmental SciencesVARIATION OF SPATHE ESSENTIAL OIL COMPOSITION OF TEN IRANIAN DATE VARIETIES (PHOENIX DACTYLIFERA L.)
International Journal of Plant, Animal and Environmental SciencesTHE ESSENTIAL OIL COMPOSITION OF SCUTELLARIA PINNATIFIDA A. HAMILT. SUBSP. MUCIDA (STAPF) RECH. F. AND COMPARISON WITH TWO OTHER SUBSPECIES IN IRAN
International Journal of Plant, Animal and Environmental SciencesEFFECT OF INCREASING SEVERITY OF DROUGHT STRESS ON MORPHOLOGY AND ESSENTIAL OIL OF POT MARIGOLD
International Journal of Plant, Animal and Environmental SciencesESSENTIAL OIL COMPOSITION OF FOUR VARIETIES OF MENTHA LONGIFOLIA L. FROM NORTHERN PARTS OF IRAN
|This article needs additional citations for verification. (October 2014)|
An essential oil is a concentrated hydrophobic liquid containing volatile aroma compounds from plants. Essential oils are also known as volatile oils, ethereal oils, aetherolea, or simply as the "oil of" the plant from which they were extracted, such as oil of clove. An oil is "essential" in the sense that it contains the "essence of" the plant's fragrance—the characteristic fragrance of the plant from which it is derived.
Essential oils are generally extracted by distillation, often by using steam. Other processes include expression or solvent extraction. They are used in perfumes, cosmetics, soaps and other products, for flavoring food and drink, and for adding scents to incense and household cleaning products.
Essential oils have been used medicinally in history. Medical applications proposed by those who sell medicinal oils range from skin treatments to remedies for cancer and often are based solely on historical accounts of use of essential oils for these purposes. Claims for the efficacy of medical treatments, and treatment of cancers in particular, are now subject to regulation in most countries.
As the use of essential oils has declined in evidence-based medicine, one must consult older textbooks for much information on their use. Modern works are less inclined to generalize; rather than refer to "essential oils" as a class at all, they prefer to discuss specific compounds, such as methyl salicylate, rather than "oil of wintergreen".
Interest in essential oils has revived in recent decades with the popularity of aromatherapy, a branch of alternative medicine that claims that essential oils and other aromatic compounds have curative effects. Oils are volatilized or diluted in a carrier oil and used in massage, diffused in the air by a nebulizer, heated over a candle flame, or burned as incense.
- 1 Production
- 2 Pharmacology
- 3 Use in aromatherapy
- 4 Dilution
- 5 Raw materials
- 6 Dangers
- 7 Standardization of its derived products
- 8 See also
- 9 Notes
- 10 References
Today, most common essential oils — such as lavender, peppermint, tea tree oil and eucalyptus — are distilled. Raw plant material, consisting of the flowers, leaves, wood, bark, roots, seeds, or peel, is put into an alembic (distillation apparatus) over water. As the water is heated, the steam passes through the plant material, vaporizing the volatile compounds. The vapors flow through a coil, where they condense back to liquid, which is then collected in the receiving vessel.
The recondensed water is referred to as a hydrosol, hydrolat, herbal distillate or plant water essence, which may be sold as another fragrant product. Popular hydrosols include rose water, lavender water, lemon balm, clary sage and orange blossom water. The use of herbal distillates in cosmetics is increasing. Some plant hydrosols have unpleasant smells and are therefore not sold.
Most citrus peel oils are expressed mechanically or cold-pressed (similar to olive oil extraction). Due to the relatively large quantities of oil in citrus peel and low cost to grow and harvest the raw materials, citrus-fruit oils are cheaper than most other essential oils. Lemon or sweet orange oils that are obtained as byproducts of the citrus industry are even cheaper.
Before the discovery of distillation, all essential oils were extracted by pressing.
Most flowers contain too little volatile oil to undergo expression; their chemical components are too delicate and easily denatured by the high heat used in steam distillation. Instead, a solvent such as hexane or supercritical carbon dioxide is used to extract the oils. Extracts from hexane and other hydrophobic solvents are called concretes, which are a mixture of essential oil, waxes, resins, and other lipophilic (oil-soluble) plant material.
Although highly fragrant, concretes contain large quantities of nonfragrant waxes and resins. Often, another solvent, such as ethyl alcohol, which is more polar in nature, is used to extract the fragrant oil from the concrete. The alcohol solution is chilled to -18C/0F for more than 48 hour which causes the waxes and lipids to precipitate out. The precipitates are then filtered out and the ethanol is removed from the remaining solution by evaporation, vacuum purge, or both, leaving behind the absolute.
Supercritical carbon dioxide is used as a solvent in supercritical fluid extraction. This method has many benefits including avoiding petrochemical residues in the product and the loss of some "top notes" when steam distillation is used. It does not yield an absolute directly. The supercritical carbon dioxide will extract both the waxes and the essential oils that make up the concrete. Subsequent processing with liquid carbon dioxide, achieved in the same extractor by merely lowering the extraction temperature, will separate the waxes from the essential oils. This lower temperature process prevents the decomposition and denaturing of compounds. When the extraction is complete, the pressure is reduced to ambient and the carbon dioxide reverts to a gas, leaving no residue.
Florasol (R134a), a refrigerant, was developed to replace Freon. Although Florasol is an "ozone-friendly" product, it is still a fluorochemical (1,1,1,2-Tetrafluoroethane) and it poses significant danger to the environment due to its global warming potential (GWP; 100-yr GWP = 1430). The European Union has banned its use, with a phase-out process beginning in 2011, to be completed in 2017  One advantage is that the extraction of essential oils occurs at or below room temperature so degradation through high temperature extremes does not occur. The essential oils are mostly pure and contain little to no foreign substances.
Estimates of total production of essential oils are difficult to obtain. One estimate, compiled from data in 1989, 1990 and 1994 from various sources, gives the following total production, in tonnes, of essential oils for which more than 1,000 tonnes were produced.
Oil Tonnes Sweet orange 12,000 Mentha arvensis 4,800 Peppermint 3,200 Cedarwood 2,600 Lemon 2,300 Eucalyptus globulus 2,070 Litsea cubeba 2,000 Clove (leaf) 2,000 Spearmint 1,300
For a video on smaller-scale domestic use production and extraction, see The Essential Series: Essential Concoction. <EupterraFoundation.com>
|This section needs more medical references for verification or relies too heavily on primary sources. (June 2014)|
Although medicinal use of essential oils is seen as pseudoscience in the healthcare community, essential oils retain considerable popular use among advocates of alternative medicine. Therefore it is difficult to obtain reliable references concerning their pharmacological merits.
Taken by mouth, many essential oils can be dangerous in high concentrations. Typical effects begin with a burning feeling, followed by salivation. In the stomach, the effect is carminative, relaxing the gastric sphincter and encouraging eructation (belching). Further down the gut, the effect typically is antispasmodic.
Typical ingredients for such applications include eucalyptus oils, menthol, capsaicin, anise and camphor. Other essential oils work well in these applications, but it is notable that others offer no significant benefit. This illustrates the fact that different essential oils may have drastically different pharmacology. Those that do work well for upper respiratory tract and bronchial problems act variously as mild expectorants and decongestants. Some act as locally anaesthetic counterirritants and, thereby, exert an antitussive effect.
Some essential oils, such as those of juniper and agathosma, are valued for their diuretic effects.[unreliable medical source?] With relatively recent concerns about the overuse of antibacterial agents, many essential oils have seen a resurgence in off-label use for such properties and are being examined for this use clinically.
Many essential oils affect the skin and mucous membranes in ways that are valuable or harmful. They are used in antiseptics and liniments in particular. Typically, they produce rubefacient irritation at first and then counterirritant numbness. Turpentine oil and camphor are two typical examples of oils that cause such effects. Menthol and some others produce a feeling of cold followed by a sense of burning. This is caused by its effect on heat-sensing nerve endings. Some essential oils, such as clove oil or eugenol, were popular for many hundred years in dentistry as antiseptics and local anaesthetics. Thymol is well known for its antiseptic effects.
Use in aromatherapy
Aromatherapy is a form of alternative medicine in which healing effects are ascribed to the aromatic compounds in essential oils and other plant extracts. Many common essential oils have medicinal properties that have been applied in folk medicine since ancient times and are still widely used today. For example, many essential oils have antiseptic properties. Many are also claimed to have an uplifting effect on the mind. Such claims, if meaningful, are not necessarily false but are difficult to quantify in the light of the sheer variability of materials used in the practice.
Essential oils are derived from sections of plants. Some plants, like the bitter orange, are sources of several types of essential oil.
Eucalyptus oil is produced from the leaves of Eucalyptus globulus. Steam-distilled eucalyptus oil is used throughout Asia, Africa, Latin America and South America as a primary cleaning/disinfecting agent added to soaped mop and countertop cleaning solutions; it also possesses insect and limited vermin control properties. Note, however, there are hundreds of species of eucalyptus, and perhaps some dozens are used to various extents as sources of essential oils. Not only do the products of different species differ greatly in characteristics and effects, but also the products of the very same tree can vary grossly.
Lavender essential oil
Lavender essential oil has long been used in the production of perfume. However, it can be estrogenic and antiandrogenic, causing problems for prepubescent boys and pregnant women, in particular. Lavender essential oil is also used as an insect repellent.
Balsam of Peru
Balsam of Peru, an essential oil derived from the Myroxylon, is used in food and drink for flavoring, in perfumes and toiletries for fragrance, and in medicine and pharmaceutical items for healing properties.[unreliable source?] However, a number of national and international surveys have identified Balsam of Peru as being in the "top five" allergens most commonly causing patch test allergic reactions in people referred to dermatology clinics.
The potential danger of an essential oil is generally relative to its level or grade of purity. Many essential oils are designed exclusively for their aroma-therapeutic quality; these essential oils generally should not be applied directly to the skin in their undiluted or "neat" form. Some can cause severe irritation, provoke an allergic reaction and, over time, prove hepatotoxic. Non-therapeutic grade essential oils are never recommended for topical or internal use.
Essential oils should not be used with animals, as they possess extreme hepatotoxicity and dermal toxicity for animals. Some essential oils, including many of the citrus peel oils, are photosensitizers, increasing the skin's vulnerability to sunlight.
Industrial users of essential oils should consult the material safety data sheets (MSDS) to determine the hazards and handling requirements of particular oils. Even certain therapeutic grade oils can pose potential threats to individuals with epilepsy or pregnant women.
Essential oils can be aggressive toward rubbers and plastics, so care must be taken in choosing the correct handling equipment. Glass syringes are often used, but have coarse volumetric graduations. Chemistry syringes are ideal, as they resist essential oils, are long enough to enter deep vessels, and have fine graduations, facilitating quality control. Unlike traditional pipettes, which have difficulty handling viscous fluids, the chemistry syringe has a seal and piston arrangement which slides inside the pipette, wiping the essential oil off the pipette wall. This improves accuracy, and the inside of the pipette is easy to clean and reuse immediately. Chemistry pipetting syringes are equal in accuracy to the best laboratory equipment and are available in sizes from 1 mL through 25 mL.
The use of essential oils in pregnancy is not recommended due to inadequate published evidence to demonstrate evidence of safety. Pregnant women often report an abnormal sensitivity to smells and taste, essential oils can cause irritation and nausea.
Estrogenic and antiandrogenic activity have been reported by in vitro study of tea tree oil and lavender essential oils. Case reports suggest the oils may be implicated in some cases of gynecomastia, an abnormal breast tissue growth, in prepubescent boys. However, these claims have been challenged [unreliable medical source?] and the European Commission’s Scientific Committee on Consumer Safety has dismissed the claims saying "Since the hormonal active ingredients of Tea Tree Oil were shown not to penetrate the skin, the hypothesized correlation of the finding of 3 cases of gynecomastia to the topical use of Tea Tree Oil is considered implausible." 
There is some concern about pesticide residues in essential oils, particularly those used therapeutically. For this reason, many practitioners of aromatherapy buy organically produced oils. Not only are pesticides present in trace quantities, but also the oils themselves are used in tiny quantities and usually in high dilutions. Where there is a concern about pesticide residues in food essential oils, such as mint or orange oils, the proper criterion is not whether the material is alleged to be organically produced, but whether it meets the government standards based on actual analysis of its pesticide content.
Essential oils are used extensively as GRAS flavoring agents in foods, beverages and confectioneries according to strict Good Manufacturing Practice (GMP) and flavorist standards. Therapeutic grade essential oils are generally safe for human consumption in small amounts. Pharmacopoeia standards for medicinal oils should be heeded. Some oils can be toxic to some domestic animals, cats in particular. The internal use of essential oils can pose hazards to pregnant women, as some can be abortifacients in dose 0.5–10 ml, and thus should not be used during pregnancy.
The flash point of each essential oil is different. Many of the common essential oils, such as tea tree, lavender, and citrus oils, are classed as a Class 3 Flammable Liquid, as they have a flash point of 50–60 °C.
The following table lists the LD50 or median lethal dose for common oils; this is the dose required to kill half the members of a tested population.LD50 is intended as a guideline only, and reported values can vary widely due to differences in tested species and testing conditions.
|Common Name||Oral LD50||Dermal LD50||Notes|
|Neem||14 g/kg||>2 g/kg|
|Lemon myrtle||2.43 g/kg||2.25 g/kg|
|Frankincense||>5 g/kg||>5 g/kg||Boswellia carterii|
|Frankincense||>2 g/kg||>2 g/kg||Boswellia sacra|
|Indian frankincense||>2 g/kg||>2 g/kg||Boswellia serrata|
|Ylang-ylang||>5 g/kg||>5 g/kg|
|Cedarwood||>5 g/kg||>5 g/kg|
|Roman chamomile||>5 g/kg||>5 g/kg|
|White camphor||>5 g/kg||>5 g/kg||Cinnamomum camphora, extracted from leaves|
|Yellow camphor||3.73 g/kg||>5 g/kg||Cinnamomum camphora, extracted from bark|
|Hot oil||3.80 g/kg||>5 g/kg||Cinnamomum camphora, oil extracted from leaves|
|Cassia||2.80 g/kg||0.32 g/kg|
It is important to understand that the foregoing figures are far less relevant in everyday life than far smaller, often localized levels of exposure. For example, a dose of many an essential oil that would do no harm if swallowed in diluted solution or emulsion, could do serious damage to eyes or lungs in a higher concentration.
Standardization of its derived products
In 2002, ISO published ISO 4720 in which the botanical names of the relevant plants are standardized. The rest of the standards with regards to this topic can be found in the section of ICS 71.100.60 
|40x40px||Wikimedia Commons has media related to Essential oils.|
- "essential oil". Oxford English Dictionary (online, American English ed.). Retrieved 2014-07-21.
- Sapeika, Norman (1963). Actions and Uses of Drugs. A.A. Balkema.[page needed]
- Thorpe's Dictionary of Applied Chemistry 8 (4th ed.). Longmans Green. 1947.[page needed]
- Gilman, A. G.; Rall, T. W.; Nies, Alan S.; Taylor, Palmer, eds. (1990). Goodman & Gilman's The Pharmacological Basis of Therapeutics (8th ed.). New York: Pergamon. ISBN 0-08-040296-8.[page needed]
- Klaassen, Curtis D.; Amdur, Mary O.; Casarett, Louis J.; Doull, John (1991). Casarett and Doull's Toxicology: The Basic Science of Poisons. New York: McGraw-Hill. ISBN 0071052399.[page needed]
- Houtsma, M.Th. (1993). E. J. Brill's First Encyclopaedia of Islam, 1913–1936 4. Brill. pp. 1011–. ISBN 9004097902.
- Forster, P et al. (2007). "Changes in Atmospheric Constituents and in Radiative Forcing" (PDF). In Solomon, S et al. Climate Change 2007: The Physical Science Basis. Contribution of Working Group I to the Fourth Assessment Report of the Intergovernmental Panel on Climate Change. Cambridge University Press.
- Refrigerant 1234YF’s Potential Impact in Automotive Applications.
- "ISO TC 54 Business Plan — Essential oils" (PDF). Retrieved 2006-09-14. It is unclear from the source what period of time the quoted figures include.
- Carroll, Robert Todd. "Aromoatherapy". The Skeptic's Dictionary (online ed.). Retrieved 6 February 2013.
- Warnke, PH; Becker, ST; Podschun, R; Sivananthan, S et al. (2009). "The battle against multi-resistant strains: Renaissance of antimicrobial essential oils as a promising force to fight hospital-acquired infections". Journal of Cranio-Maxillofacial Surgery 37 (7): 392–7. PMID 19473851. doi:10.1016/j.jcms.2009.03.017.
- Haneke, Karen E (February 2002), Turpentine (Turpentine Oil, Wood Turpentine, Sulfate Turpentine, Sulfite Turpentine) [8006-64-2]: Review of Toxicological Literature (PDF) (Contract No. N01-ES-65402), National Institute of Environmental Health Sciences[page needed]
- Watt, John Mitchell; Breyer-Brandwijk, Maria Gerdina (1962). The Medicinal and Poisonous Plants of Southern and Eastern Africa (2nd ed.). Edinburgh: E & S Livingstone.[page needed]
- Levy, SB (June 2001). "Antibacterial household products: Cause for concern" (PDF). Emerging Infectious Diseases (conference presentation) 7 (3 Suppl.): 512–5.
- Singh, G; Kapoor, IPS; Pandey, SK; Singh, UK et al. (2002). "Studies on essential oils: Part 10; Antibacterial activity of volatile oils of some spices". Phytotherapy Research 16 (7): 680–2. PMID 12410554. doi:10.1002/ptr.951.
- Prabuseenivasan, S; Jayakumar, M; Ignacimuthu, S (November 30, 2006). "In vitro antibacterial activity of some plant essential oils". BMC Complementary and Alternative Medicine 6: 39. PMC 1693916. PMID 17134518. doi:10.1186/1472-6882-6-39.
- N. Groom. New Perfume Handbook. Springer Science & Business Media, 1997 ISBN 9780751404036, pp. 184-186
- Henley, DV; Lipson, N; Korach, KS; Bloch, CA (2007). "Prepubertal gynecomastia linked to lavender and tea tree oils". New England Journal of Medicine 356 (5): 479–85. PMID 17267908. doi:10.1056/NEJMoa064725.
- Debboun, Mustapha; Frances, Stephen P.; Strickman, Daniel, eds. (2014). Insect Repellents Handbook (2nd ed.). CRC Press. p. 362. ISBN 1466553553.
- "Balsam, Peru". www.hippylife.co.uk. Hippylife. Retrieved 2006-08-17.
- Arenholt-Bindslev, D; Jolanki, R; Kanerva, L (2008). "Diagnosis of Side Effects of Dental Materials, with Special Emphasis on Delayed and Immediate Allergic Reactions". In Schmalz, Gottfried; Arenholt-Bindslev, Dorthe. Biocompatibility of Dental Materials. Springer. p. 352. ISBN 9783540777823. doi:10.1007/978-3-540-77782-3_14. Retrieved March 5, 2014.
- Habif, Thomas P. (2009). Clinical Dermatology. Elsevier Health Sciences. ISBN 9780323080378. Retrieved March 6, 2014.
- Yiannias, JA (2013). "Contact Dermatitis". In Bope, Edward T.; Kellerman, Rick D. Conn's Current Therapy 2014: Expert Consult. Elsevier Health Sciences. ISBN 9780323225724. Retrieved March 6, 2014.
- Liu, H; Bai, Y; Hong, Y; Zhang, X (June 2010). "[Component analysis and acute hepatotoxicity of volatile oils from argy wormwood leaf extracted by different methods]". Zhongguo Zhong Yao Za Zhi (in 中文) 35 (11): 1439–46. PMID 20822017.
- Kaddu, S; Kerl, H; Wolf, P (2001). "Accidental bullous phototoxic reactions to bergamot aromatherapy oil". Journal of the American Academy of Dermatology 45 (3): 458–61. PMID 11511848. doi:10.1067/mjd.2001.116226.
- Nordin, S; Broman, DA; Olofsson, JK; Wulff, M (2004). "A longitudinal descriptive study of self-reported abnormal smell and taste perception in pregnant women". Chemical Senses 29 (5): 391–402. PMID 15201206. doi:10.1093/chemse/bjh040.
- Henley, DV; Lipson, N; Korach, KS; Bloch, CA (2007). "Prepubertal gynecomastia linked to lavender and tea tree oils". New England Journal of Medicine 356 (5): 479–85. PMID 17267908. doi:10.1056/NEJMoa064725.
- "Oils make male breasts develop". BBC News. February 1, 2007. Retrieved September 9, 2007.
- Carson, CF; Tisserand, R; Larkman, T (April 2014). "Lack of evidence that essential oils affect puberty". Reproductive Toxicology (letter to the editor) 44: 50–1. PMID 24556344. doi:10.1016/j.reprotox.2013.09.010.
- Scientific Committee on Consumer Products (December 16, 2008), Opinion on tea tree oil (PDF) (Report No. SCCP/1155/08), Directorate-General for Health and Consumers: European Commission: European Union
- Menary, RC (2008). Minimising pesticide residues in essential oils. Rural Industries Research and Development Corporation. ISBN 9781741517095.[page needed]
- Bischoff, K; Guale, F (April 1998). "Australian tea tree (Melaleuca alternifolia) oil poisoning in three purebred cats". J. Vet. Diagn. Invest. 10 (2): 208–10. PMID 9576358. doi:10.1177/104063879801000223.
- Dweck, AC (September 2009). "Toxicology of essential oils reviewed" (PDF). Personal Care.
- International Organization for Standardization. "ISO 4720:2002 Essential oils — Nomenclature". Retrieved April 23, 2009.
- International Organization for Standardization. "71.100.60: Essential oils". Retrieved June 14, 2009.
- Kurt Schnaubelt (1999). Advanced Aromatherapy: The Science of Essential Oil Therapy. Healing Arts Press. ISBN 0-89281-743-7.
- Wanda Sellar (2001). The Directory of Essential Oils (Reprint ed.). Essex: The C.W. Daniel Company, Ltd. ISBN 0-85207-346-1.
- Robert Tisserand (1995). Essential Oil Safety: A Guide for Health Care Professionals. Churchill Livingstone. ISBN 0-443-05260-3.
- K.H.C. Baser and G. Buchbauer (2010). Handbook of Essential Oils: Science, Technology and Applications. CRC Press, Boca Raton, London, New York. ISBN 978-1-4200-6315-8.
Lua error in Module:Authority_control at line 346: attempt to index field 'wikibase' (a nil value).