Open Access Articles- Top Results for Ethylone


Systematic (IUPAC) name
Clinical data
  • N (US)
  • schedule 1, positional isomer of butylone
Oral, nasal, IV
ChemSpider 21106271 7pxN
Chemical data
Formula C12H15NO3
221.2524 g/mol
 14pxN (what is this?)  (verify)

Ethylone, also known as 3,4-methylenedioxy-N-ethylcathinone (MDEC, bk-MDEA), is recreational designer drug classified as an entactogen, stimulant, and psychedelic of the phenethylamine, amphetamine, and cathinone chemical classes. It is the β-keto analogue of MDEA ("Eve"). Ethylone has only a short history of human use and is reported to be less potent than its relative methylone.[citation needed] In the United States, it began to be found in cathinone products in late 2011.[1]

Very little data exists about the pharmacological properties, metabolism, and toxicity of ethylone, but several ethylone-related deaths have been reported..[1]


Analysis of human and rat urine for the metabolites of bk-amphetamines suggested that ethylone was degraded in the following metabolic steps:[2]

  1. N-deethylation to the primary amine.
  2. Reduction of the keto moiety to the respective alcohol.

See also


  1. ^ a b Journal of Analytical Toxicology. doi:10.1093/jat/bkv053.  Missing or empty |title= (help)
  2. ^ Meyer, Markus R; Jens Wilhelm; Frank T. Peters; Hans H. Maurer (2010). "Beta-keto amphetamines: studies on the metabolism of the designer drug mephedrone and toxicological detection of mephedrone, butylone, and methylone in urine using gas chromatography–mass spectrometry". Analytical and Bioanalytical Chemistry 397 (3): 1225–1233. PMID 20333362. doi:10.1007/s00216-010-3636-5. Retrieved 19 September 2012. 

External links

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