Adverts

Open Access Articles- Top Results for Excitatory amino-acid transporter 4

Excitatory amino-acid transporter 4

Template:Infobox3cols/rowTemplate:Infobox3cols/rowTemplate:Infobox3cols/rowTemplate:Infobox3cols/row
Identifiers
SymbolsSLC1A6 ; EAAT4
External IDsOMIM600637 MGI1096331 HomoloGene21055 IUPHAR: 871 ChEMBL: 3173 GeneCards: SLC1A6 Gene
Orthologs
SpeciesHumanMouse
Entrez651120513
EnsemblENSG00000105143ENSMUSG00000005357
UniProtP48664O35544
RefSeq (mRNA)NM_001272087NM_009200
RefSeq (protein)NP_001259016NP_033226
Location (UCSC)Chr 19:
15.06 – 15.13 Mb
Chr 10:
78.78 – 78.81 Mb
PubMed search[1][2]

Excitatory amino-acid transporter 4 (EAAT4) is a protein that in humans is encoded by the SLC1A6 gene.[1][2]

EAAT4 is expressed predominantly in the cerebellum, has high affinity for the excitatory amino acids L-aspartate and L-glutamate. When stimulated by these amino acids, EAAT4 conducts chloride ions.[2]

References

  1. ^ "Entrez Gene: solute carrier family 1 (high affinity aspartate/glutamate transporter)". 
  2. ^ a b Fairman WA, Vandenberg RJ, Arriza JL, Kavanaugh MP, Amara SG (June 1995). "An excitatory amino-acid transporter with properties of a ligand-gated chloride channel". Nature 375 (6532): 599–603. PMID 7791878. doi:10.1038/375599a0. 

Further reading

</dl>

Template:Gene-19-stub