Open Access Articles- Top Results for FHL3


SymbolsFHL3 ; SLIM2
External IDsOMIM602790 MGI1341092 HomoloGene37928 GeneCards: FHL3 Gene
RNA expression pattern
File:PBB GE FHL3 218818 at tn.png
More reference expression data
RefSeq (mRNA)NM_001243878NM_010213
RefSeq (protein)NP_001230807NP_034343
Location (UCSC)Chr 1:
38.46 – 38.47 Mb
Chr 4:
124.7 – 124.71 Mb
PubMed search[1][2]

Four and a half LIM domains protein 3 is a protein that in humans is encoded by the FHL3 gene.[1][2][3]

LIM proteins are defined by the possession of a highly conserved double zinc finger motif called the LIM domain.[supplied by OMIM][3]


FHL3 has been shown to interact with:


  1. ^ Morgan MJ, Madgwick AJ (October 1996). "Slim defines a novel family of LIM-proteins expressed in skeletal muscle". Biochem Biophys Res Commun 225 (2): 632–8. PMID 8753811. doi:10.1006/bbrc.1996.1222. 
  2. ^ Lee SM, Tsui SK, Chan KK, Kotaka M, Li HY, Chim SS et al. (May 1999). "Chromosomal mapping of a skeletal muscle specific LIM-only protein FHL3 to the distal end of the short arm of human chromosome 1". Somat Cell Mol Genet 24 (3): 197–202. PMID 10226657. doi:10.1023/B:SCAM.0000007122.03392.4b. 
  3. ^ a b "Entrez Gene: FHL3 four and a half LIM domains 3". 
  4. ^ a b Fimia GM, De Cesare D, Sassone-Corsi P (November 2000). "A family of LIM-only transcriptional coactivators: tissue-specific expression and selective activation of CREB and CREM". Mol. Cell. Biol. 20 (22): 8613–22. PMC 102166. PMID 11046156. doi:10.1128/mcb.20.22.8613-8622.2000. 
  5. ^ a b Turner J, Nicholas H, Bishop D, Matthews JM, Crossley M (April 2003). "The LIM protein FHL3 binds basic Krüppel-like factor/Krüppel-like factor 3 and its co-repressor C-terminal-binding protein 2". J. Biol. Chem. 278 (15): 12786–95. PMID 12556451. doi:10.1074/jbc.M300587200. 
  6. ^ Li HY, Ng EK, Lee SM, Kotaka M, Tsui SK, Lee CY et al. "Protein-protein interaction of FHL3 with FHL2 and visualization of their interaction by green fluorescent proteins (GFP) two-fusion fluorescence resonance energy transfer (FRET)". J. Cell. Biochem. 80 (3): 293–303. PMID 11135358. doi:10.1002/1097-4644(20010301)80:3<293::aid-jcb10>;2-l. 
  7. ^ Samson T, Smyth N, Janetzky S, Wendler O, Müller JM, Schüle R et al. (July 2004). "The LIM-only proteins FHL2 and FHL3 interact with alpha- and beta-subunits of the muscle alpha7beta1 integrin receptor". J. Biol. Chem. 279 (27): 28641–52. PMID 15117962. doi:10.1074/jbc.M312894200. 

Further reading


External links

This article incorporates text from the United States National Library of Medicine, which is in the public domain.

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