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FOSL2

Template:Infobox3cols/rowTemplate:Infobox3cols/rowTemplate:Infobox3cols/rowTemplate:Infobox3cols/row
Identifiers
SymbolsFOSL2 ; FRA2
External IDsOMIM601575 MGI102858 HomoloGene3845 GeneCards: FOSL2 Gene
RNA expression pattern
File:PBB GE FOSL2 205409 at tn.png
File:PBB GE FOSL2 218880 at tn.png
File:PBB GE FOSL2 218881 s at tn.png
More reference expression data
Orthologs
SpeciesHumanMouse
Entrez235514284
EnsemblENSG00000075426ENSMUSG00000029135
UniProtP15408P47930
RefSeq (mRNA)NM_005253NM_008037
RefSeq (protein)NP_005244NP_032063
Location (UCSC)Chr 2:
28.62 – 28.64 Mb
Chr 5:
32.14 – 32.16 Mb
PubMed search[1][2]

Fos-related antigen 2 is a protein that in humans is encoded by the FOSL2 gene.[1]

The Fos gene family consists of 4 members: FOS, FOSB, FOSL1, and FOSL2. These genes encode leucine zipper proteins that can dimerize with proteins of the JUN family, thereby forming the transcription factor complex AP-1. As such, the FOS proteins have been implicated as regulators of cell proliferation, differentiation, and transformation.[1]

See also

References

Further reading

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External links

This article incorporates text from the United States National Library of Medicine, which is in the public domain.

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