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FZD10

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Identifiers
SymbolsFZD10 ; CD350; FZ-10; Fz10; FzE7; hFz10
External IDsOMIM606147 MGI2136761 HomoloGene21411 IUPHAR: 238 GeneCards: FZD10 Gene
RNA expression pattern
File:PBB GE FZD10 219764 at tn.png
More reference expression data
Orthologs
SpeciesHumanMouse
Entrez1121193897
EnsemblENSG00000111432ENSMUSG00000081683
UniProtQ9ULW2Q8BKG4
RefSeq (mRNA)NM_007197NM_175284
RefSeq (protein)NP_009128NP_780493
Location (UCSC)Chr 12:
130.65 – 130.65 Mb
Chr 5:
128.6 – 128.6 Mb
PubMed search[1][2]

Frizzled-10 is a protein that in humans is encoded by the FZD10 gene.[1][2] FZD10 has also been designated as CD350 (cluster of differentiation 350).

This gene is a member of the frizzled gene family. Members of this family encode 7-transmembrane domain proteins that are receptors for the Wingless type MMTV integration site family of signaling proteins. Most frizzled receptors are coupled to the beta-catenin canonical signaling pathway. Using array analysis, expression of this intronless gene is significantly up-regulated in two cases of primary colon cancer.[2]

See also

References

  1. Koike J, Takagi A, Miwa T, Hirai M, Terada M, Katoh M (Sep 1999). "Molecular cloning of Frizzled-10, a novel member of the Frizzled gene family". Biochem Biophys Res Commun 262 (1): 39–43. PMID 10448064. doi:10.1006/bbrc.1999.1161. 
  2. 2.0 2.1 "Entrez Gene: FZD10 frizzled homolog 10 (Drosophila)". 

Further reading

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External links

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