Open Access Articles- Top Results for Farampator


Systematic (IUPAC) name
Clinical data
  • Investigational New Medicine
211735-76-1 7pxY
PubChem CID 4118151
ChemSpider 3331565 7pxN
UNII 7X6P5N8K2L 7pxN
KEGG D04131 7pxY
Synonyms Farampator, CX-691
Chemical data
Formula C12H13N3O2
231.25052 g/mol
 14pxN (what is this?)  (verify)

Farampator (CX-691, Org 24448) is an ampakine drug. It was developed by Cortex Pharmaceuticals, and licensed to Organon BioSciences for commercial development. Following the purchase of Organon by Schering-Plough in 2007, the development license to farampator has been transferred, and development is continuing.

Farampator has been investigated for its effect on AMPA receptors and researched for potential use in the treatment of schizophrenia and Alzheimer's Disease. It was found to improve short-term memory, but impaired episodic memory. It produced side effects (SEs) such as headache, somnolence and nausea. Subjects with SEs had significantly higher plasma levels of farampator than subjects without SEs. Additional analyses revealed that in the farampator condition the group without SEs showed a significantly superior memory performance relative to the group with SEs. [1]


  1. ^ Wezenberg E, Verkes RJ, Ruigt GS, Hulstijn W, Sabbe BG. Acute effects of the ampakine farampator on memory and information processing in healthy elderly volunteers. Neuropsychopharmacology. 2007 Jun;32(6):1272-83. doi:10.1038/sj.npp.1301257 PMID 17119538

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