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Fasiplon

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Fasiplon
200px
Systematic (IUPAC) name
6-Ethyl-7-methoxy-5-methyl-2-(5-methyl-[1,2,4]oxadiazol-3-yl)-imidazo[1,2-a]pyrimidine
Clinical data
Identifiers
106100-65-6 7pxY
None
PubChem CID 208954
ChemSpider 181047 7pxN
UNII XCA050IPGB 7pxY
Chemical data
Formula C13H15N5O2
273.290 g/mol
 14pxN (what is this?)  (verify)

Fasiplon (RU 33203) is a nonbenzodiazepine anxiolytic drug from the imidazopyrimidine family of drugs.

Fasiplon binds strongly to benzodiazepine sites on the GABAA receptor and has similar anxiolytic effects in animals, but with less sedative or muscle relaxant action.[1] It was developed by a team at Roussel Uclaf in the 1990s[2]

References

  1. ^ Tully WR, Gardner CR, Gillespie RJ, Westwood R (July 1991). "2-(oxadiazolyl)- and 2-(thiazolyl)imidazo[1,2-a]pyrimidines as agonists and inverse agonists at benzodiazepine receptors". Journal of Medicinal Chemistry 34 (7): 2060–7. PMID 1648620. doi:10.1021/jm00111a021. 
  2. ^ US Patent 5869481 Anticonvulsive 1-ar(alk)ylimidazolin-2-ones and process for making