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Open Access Articles- Top Results for Fenoprofen

Fenoprofen

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Fenoprofen
File:Fenoprofen2DACS.svg
File:Fenoprofen-3D-balls.png
Systematic (IUPAC) name
2-(3-phenoxyphenyl)propanoic acid
Clinical data
AHFS/Drugs.com monograph
MedlinePlus a681026
  • US: D (Evidence of risk)
  • C
Oral
Pharmacokinetic data
Metabolism Major urinary metabolites are fenoprofen glucuronide and 4′-hydroxyfenoprofen glucuronide.
Half-life 3 hours
Excretion Renal (~90%)
Identifiers
29679-58-1 7pxY
M01AE04
PubChem CID 3342
DrugBank DB00573 7pxY
ChemSpider 3225 7pxY
UNII RA33EAC7KY 7pxY
KEGG D02350 7pxY
ChEBI CHEBI:5004 7pxY
ChEMBL CHEMBL1297 7pxY
Chemical data
Formula C15H14O3
242.26986 g/mol
 14pxY (what is this?)  (verify)

Fenoprofen is a non-steroidal anti-inflammatory drug. Fenoprofen calcium is used for symptomatic relief for rheumatoid arthritis, osteoarthritis, and mild to moderate pain. Fenoprofen is marketed in the USA as Nalfon.

Pharmacology

Decreases inflammation, pain, and fever, probably through inhibition of cyclooxygenase activity and prostaglandin synthesis.

Contraindications

History of significantly impaired renal function; patients with known hypersensitivity to any component of the product; patients who have experienced asthma, urticaria, or allergic-type reactions after taking aspirin or other NSAIDs; treatment of perioperative pain in the setting of coronary artery bypass graft (CABG) surgery.

Drug interactions

Laboratory test interactions

False elevation in free and total serum T 3 as measured by Amerlex-M kit.

Brand names

References