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Fenticonazole

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Fenticonazole
File:Fenticonazole.png
Systematic (IUPAC) name
1-[2-(2,4-dichlorophenyl)-2-{[4-(phenylsulfanyl)phenyl]methoxy}ethyl]-1H-imidazole
Clinical data
AHFS/Drugs.com International Drug Names
  • prescription
ovule, spray, cream
Identifiers
72479-26-6 7pxY
D01AC12 G01AF12
PubChem CID 51755
ChemSpider 46840 7pxN
UNII QG05NRB077 7pxY
KEGG D02582 7pxY
ChEBI CHEBI:82863 7pxN
Chemical data
Formula C24H20Cl2N2OS
455.4 g/mol
 14pxN (what is this?)  (verify)

Fenticonazole is an azole antifungal drug, used locally as the nitrate in the treatment of vulvovaginal candidiasis. It is active against a range of organisms including dermatophyte pathogens, Malassezia furfur, and Candida albicans.

Uses and administration

A 200-mg pessary is inserted into the vagina at bedtime for 3 nights or a 600-mg pessary is inserted once only at bedtime. Fenticonazole nitrate is also applied topically as a 2% cream or solution for the treatment of fungal skin infections.

Adverse effects

Burning and itching have been reported after the application of fenticonazole nitrate.

Intravaginal preparations of fenticonazole may damage latex contraceptives and additional contraceptive measures are therefore necessary during local administration.

References

  • The Merck Index, 12th Edition. 4047
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