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Flaviviridae

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Flaviviruses
Virus classification
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The Flaviviridae are a family of viruses that are primarily spread through arthropod vectors (mainly ticks and mosquitoes). The family gets its name from Yellow Fever virus, a type virus of Flaviviridae; flavus means yellow in Latin. (Yellow fever in turn was named because of its propensity to cause jaundice in victims.)[1]

Flaviviridae have monopartite, linear, single-stranded RNA genomes of positive polarity, 9.6 to 12.3 kilobase in length. The 5'-termini of flaviviruses carry a methylated nucleotide cap, while other members of this family are uncapped and encode an internal ribosome entry site. Virus particles are enveloped and spherical, about 40–60 nm in diameter.

Taxonomy

This family includes the following genera:

Clinical importance

Major diseases caused by the Flaviviridae family include:

References

  1. ^ "Flaviviridae". Microbe Wiki. Retrieved July 22, 2008. 
  2. ^ Paula T, Pablo R, Eugenia V, Pablo B, Sabino P, José M et al. (2009). "New drug targets for hepatitis C and other Flaviviridae viruses". Infect Disord Drug Targets 9 (2): 133–47. PMID 19275702. doi:10.2174/187152609787847749. 

External links