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Open Access Articles- Top Results for Fluroxene

Fluroxene

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Fluroxene
File:Fluroxene.svg
Systematic (IUPAC) name
(2,2,2-trifluoroethoxy)ethene
Clinical data
Identifiers
406-90-6
None
PubChem CID 9844
ChemSpider 9461
Chemical data
Formula C4H5F3O
126.077 g/mol

Fluroxene (INN, USAN; brand name Fluoromar), or 2,2,2-trifluoroethyl vinyl ether, is a volatile, inhalational anesthetic, and was the first halogenated hydrocarbon anesthetic to be introduced.[1][2] It was synthesized in 1951, and was introduced for clinical use in 1954, but was voluntarily withdrawn from the market in 1974 due to its potential flammability and accumulating evidence that it could cause organ toxicity.[2][1][3] In any case, prior to being discontinued, it had largely been superseded by halothane.[4]

See also

References

  1. ^ a b Robert K. Stoelting; Simon C. Hillier (11 January 2012). Pharmacology and Physiology in Anesthetic Practice. Lippincott Williams & Wilkins. pp. 142–. ISBN 978-1-4511-6583-8. 
  2. ^ a b Paul G Barash; Bruce F Cullen; Robert K Stoelting; Michael Cahalan; M Christine Stock (1 January 2011). Clinical Anesthesia. Lippincott Williams & Wilkins. pp. 113–. ISBN 978-1-4511-2297-8. 
  3. ^ Monte Lichtiger; Frank Moya (1 January 1978). Introduction to the practice of anesthesia. Medical Dept., Harper & Row. ISBN 978-0-06-141534-0. 
  4. ^ Acta anaesthesiologica Belgica. Acta Medica Belgica. 1974. 



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