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Fosfluconazole

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Fosfluconazole
File:Fosfluconazol.svg
Systematic (IUPAC) name
{[2-(2,4-Difluorophenyl)-1,3-bis(1H-1,2,4-triazol-1-yl)propan-2-yl]oxy}phosphonic acid
Clinical data
AHFS/Drugs.com International Drug Names
  • (Prescription only)
IV
Identifiers
 7pxY
None
PubChem CID 214356
ChemSpider 185843 7pxY
UNII 3JIJ299EWH 7pxY
ChEMBL CHEMBL1908301 7pxY
Chemical data
Formula C13H13F2N6O4P
386.25 g/mol
 14pxN (what is this?)  (verify)

Fosfluconazole (INN) is a water-soluble phosphate prodrug of fluconazole - a triazole antifungal drug used in the treatment and prevention of superficial and systemic fungal infections. The phosphate ester bond is hydrolysed by the action of a phosphatase - an enzyme that removes a phosphate group from its substrate by hydrolysing phosphoric acid monoesters into a phosphate ion and a molecule with a free hydroxyl group (see dephosphorylation).


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