Open Access Articles- Top Results for GBLD-345


File:GBLD-345 structure.png
Systematic (IUPAC) name
2-(4-aminophenyl)-3-methoxy-N-[(3-methoxyphenyl)methyl] imidazo[2,1-f]pyridazin-6-amine
Clinical data
PubChem CID 4602899
Chemical data
Formula C21H21N5O2
375.423 g/mol
 14pxY (what is this?)  (verify)

GBLD-345 is an anxiolytic drug used in scientific research, which acts as a non-selective, full-efficacy positive allosteric modulator of the GABAA receptor. It has similar effects to benzodiazepine drugs, but is structurally distinct and so is classed as a nonbenzodiazepine anxiolytic.[1]


  1. Davies LP, Barlin GB, Ireland SJ, Ngu MM (October 1992). "Substituted imidazo[1,2-b]pyridazines. New compounds with activity at central and peripheral benzodiazepine receptors". Biochemical Pharmacology 44 (8): 1555–61. PMID 1358075. doi:10.1016/0006-2952(92)90472-U. 

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